Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third
ObjectiveThe resection of parasagittal and falx meningiomas in the middle third superior sagittal sinus (SSS) is associated with a high risk of postoperative motor deficits. This study discusses the risk factors affecting postoperative motor decline and recovery of motor function after follow-up.Met...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-02-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1458934/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832542353696489472 |
|---|---|
| author | Chengxuan Guo Yafei Xue Yang Li Qilong Tian Yan Qu Qing Cai |
| author_facet | Chengxuan Guo Yafei Xue Yang Li Qilong Tian Yan Qu Qing Cai |
| author_sort | Chengxuan Guo |
| collection | DOAJ |
| description | ObjectiveThe resection of parasagittal and falx meningiomas in the middle third superior sagittal sinus (SSS) is associated with a high risk of postoperative motor deficits. This study discusses the risk factors affecting postoperative motor decline and recovery of motor function after follow-up.MethodsThe results of a single-institution retrospective cohort study of parasagittal and falx meningioma resection in the middle third between 2016 and 2023 were reviewed, and parameters were screened as potential predictors. Variables of interest included postoperative motor decline and outcome after follow-up. Univariate and multivariate analyses were performed to identify risk factors.ResultsAmong 87 patients who underwent resection of parasagittal (63.2%) or falx (36.8%) middle third meningiomas, 14.9% (13/87) experienced postoperative motor decline. Among the 36 patients (41.4%) with preoperative motor deficits, 66.3% improved, 17.0% unchanged, and 16.7% (6/36) worsened following surgery. Among the 51 patients without preoperative motor deficits, 13.7% (7/51) developed new weakness. The predictors of postoperative motor decline were major venous involvement (p = 0.022), falx meningioma (p = 0.031), loss of the brain-tumor interface (p=0.033) and WHO grade II-III (p = 0.032).ConclusionsThe resection of parasagittal and falx meningiomas in the middle third carries a high rate of postoperative morbidity and deserves perioperative planning. Alternative surgical strategies, such as preserving the brain-tumor arachnoid interface and minority residual tumors, may prevent motor decline in a subset of high-risk patients. |
| format | Article |
| id | doaj-art-0bed09439209496ea0a538b0ee251995 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-0bed09439209496ea0a538b0ee2519952025-02-04T05:28:12ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-02-011510.3389/fonc.2025.14589341458934Risk factors for motor decline following parasagittal and falx meningioma resection in the middle thirdChengxuan GuoYafei XueYang LiQilong TianYan QuQing CaiObjectiveThe resection of parasagittal and falx meningiomas in the middle third superior sagittal sinus (SSS) is associated with a high risk of postoperative motor deficits. This study discusses the risk factors affecting postoperative motor decline and recovery of motor function after follow-up.MethodsThe results of a single-institution retrospective cohort study of parasagittal and falx meningioma resection in the middle third between 2016 and 2023 were reviewed, and parameters were screened as potential predictors. Variables of interest included postoperative motor decline and outcome after follow-up. Univariate and multivariate analyses were performed to identify risk factors.ResultsAmong 87 patients who underwent resection of parasagittal (63.2%) or falx (36.8%) middle third meningiomas, 14.9% (13/87) experienced postoperative motor decline. Among the 36 patients (41.4%) with preoperative motor deficits, 66.3% improved, 17.0% unchanged, and 16.7% (6/36) worsened following surgery. Among the 51 patients without preoperative motor deficits, 13.7% (7/51) developed new weakness. The predictors of postoperative motor decline were major venous involvement (p = 0.022), falx meningioma (p = 0.031), loss of the brain-tumor interface (p=0.033) and WHO grade II-III (p = 0.032).ConclusionsThe resection of parasagittal and falx meningiomas in the middle third carries a high rate of postoperative morbidity and deserves perioperative planning. Alternative surgical strategies, such as preserving the brain-tumor arachnoid interface and minority residual tumors, may prevent motor decline in a subset of high-risk patients.https://www.frontiersin.org/articles/10.3389/fonc.2025.1458934/fullmiddle thirdfalx meningiomamotor declinerisk factorparasagittal meningiomas |
| spellingShingle | Chengxuan Guo Yafei Xue Yang Li Qilong Tian Yan Qu Qing Cai Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third Frontiers in Oncology middle third falx meningioma motor decline risk factor parasagittal meningiomas |
| title | Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third |
| title_full | Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third |
| title_fullStr | Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third |
| title_full_unstemmed | Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third |
| title_short | Risk factors for motor decline following parasagittal and falx meningioma resection in the middle third |
| title_sort | risk factors for motor decline following parasagittal and falx meningioma resection in the middle third |
| topic | middle third falx meningioma motor decline risk factor parasagittal meningiomas |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1458934/full |
| work_keys_str_mv | AT chengxuanguo riskfactorsformotordeclinefollowingparasagittalandfalxmeningiomaresectioninthemiddlethird AT yafeixue riskfactorsformotordeclinefollowingparasagittalandfalxmeningiomaresectioninthemiddlethird AT yangli riskfactorsformotordeclinefollowingparasagittalandfalxmeningiomaresectioninthemiddlethird AT qilongtian riskfactorsformotordeclinefollowingparasagittalandfalxmeningiomaresectioninthemiddlethird AT yanqu riskfactorsformotordeclinefollowingparasagittalandfalxmeningiomaresectioninthemiddlethird AT qingcai riskfactorsformotordeclinefollowingparasagittalandfalxmeningiomaresectioninthemiddlethird |