Modelling the impact of environmental and social determinants on mental health using generative agents

Abstract Mental health is shaped by socio-environmental determinants, yet traditional research approaches struggle to capture their complex interactions. This review explores the potential of generative agents, powered by large language models, to simulate human-like behaviour in virtual environment...

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Main Authors: Joseph Kambeitz, Andreas Meyer-Lindenberg
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-024-01422-z
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author Joseph Kambeitz
Andreas Meyer-Lindenberg
author_facet Joseph Kambeitz
Andreas Meyer-Lindenberg
author_sort Joseph Kambeitz
collection DOAJ
description Abstract Mental health is shaped by socio-environmental determinants, yet traditional research approaches struggle to capture their complex interactions. This review explores the potential of generative agents, powered by large language models, to simulate human-like behaviour in virtual environments for mental health research. We outline potential applications including the modelling of adverse life events, urbanicity, climate change, discuss potential challenges and describe how generative agents could transform mental health research.
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spelling doaj-art-0beabae452554476a3106b7cf2aa80d02025-01-19T12:39:51ZengNature Portfolionpj Digital Medicine2398-63522025-01-01811810.1038/s41746-024-01422-zModelling the impact of environmental and social determinants on mental health using generative agentsJoseph Kambeitz0Andreas Meyer-Lindenberg1Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital, University of CologneDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of HeidelbergAbstract Mental health is shaped by socio-environmental determinants, yet traditional research approaches struggle to capture their complex interactions. This review explores the potential of generative agents, powered by large language models, to simulate human-like behaviour in virtual environments for mental health research. We outline potential applications including the modelling of adverse life events, urbanicity, climate change, discuss potential challenges and describe how generative agents could transform mental health research.https://doi.org/10.1038/s41746-024-01422-z
spellingShingle Joseph Kambeitz
Andreas Meyer-Lindenberg
Modelling the impact of environmental and social determinants on mental health using generative agents
npj Digital Medicine
title Modelling the impact of environmental and social determinants on mental health using generative agents
title_full Modelling the impact of environmental and social determinants on mental health using generative agents
title_fullStr Modelling the impact of environmental and social determinants on mental health using generative agents
title_full_unstemmed Modelling the impact of environmental and social determinants on mental health using generative agents
title_short Modelling the impact of environmental and social determinants on mental health using generative agents
title_sort modelling the impact of environmental and social determinants on mental health using generative agents
url https://doi.org/10.1038/s41746-024-01422-z
work_keys_str_mv AT josephkambeitz modellingtheimpactofenvironmentalandsocialdeterminantsonmentalhealthusinggenerativeagents
AT andreasmeyerlindenberg modellingtheimpactofenvironmentalandsocialdeterminantsonmentalhealthusinggenerativeagents