TCR-T cell therapy for solid tumors: challenges and emerging solutions

TCR-T cell therapy for solid tumors: challenges and emerging solutions

With the use of T cell receptor T cells (TCR-T cells) and chimeric antigen receptor T cells (CAR-T cells), T-cell immunotherapy for cancer has advanced significantly in recent years. CAR-T cell therapy has demonstrated extraordinary success when used to treat hematologic malignancies. Nevertheless,...

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Bibliographic Details
Main Authors: Wanjun He, Kai Cui, Muhammad Asad Farooq, Na Huang, Songshan Zhu, Dan Jiang, Xiqian Zhang, Jian Chen, Yinxia Liu, Guangxian Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
adoptive cell therapy
immunotherapy
solid tumor
TCR
TCR-T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1493346/full
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