Gender Differences in Behçet’s Disease Associated Uveitis
Behçet’s disease is a systemic vasculitis of unknown etiology, characterized by oral and genital ulceration, skin lesions, and uveitis as well as vascular, central nervous system, and gastrointestinal system involvement. It is prevalent in the Middle East, Mediterranean, and Eastern Asia. The aim of...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/820710 |
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| author | Didar Ucar-Comlekoglu Austin Fox H. Nida Sen |
| author_facet | Didar Ucar-Comlekoglu Austin Fox H. Nida Sen |
| author_sort | Didar Ucar-Comlekoglu |
| collection | DOAJ |
| description | Behçet’s disease is a systemic vasculitis of unknown etiology, characterized by oral and genital ulceration, skin lesions, and uveitis as well as vascular, central nervous system, and gastrointestinal system involvement. It is prevalent in the Middle East, Mediterranean, and Eastern Asia. The aim of this review is to evaluate the gender differences in clinical manifestations of Behçet’s disease, treatment responses, mortality, and morbidity. Behçet’s disease has been reported to be more prevalent in males from certain geographic regions and particular ethnic groups; however, recent reports indicate more even gender distribution across the world. There are gender differences in clinical manifestations and severity of the disease. Ocular manifestations, vascular involvement, and neurologic symptoms are more frequently reported in male patients whereas oral and genital ulcers, skin lesions, and arthritis occur more frequently in female patients. The disease can have a more severe course in males, and overall mortality rate is significantly higher among young male patients. |
| format | Article |
| id | doaj-art-0b7abe3d626049b68eaffdf37659c92f |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-0b7abe3d626049b68eaffdf37659c92f2025-02-03T05:59:45ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/820710820710Gender Differences in Behçet’s Disease Associated UveitisDidar Ucar-Comlekoglu0Austin Fox1H. Nida Sen2National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USANational Eye Institute, National Institutes of Health, Bethesda, MD 20892, USANational Eye Institute, National Institutes of Health, Bethesda, MD 20892, USABehçet’s disease is a systemic vasculitis of unknown etiology, characterized by oral and genital ulceration, skin lesions, and uveitis as well as vascular, central nervous system, and gastrointestinal system involvement. It is prevalent in the Middle East, Mediterranean, and Eastern Asia. The aim of this review is to evaluate the gender differences in clinical manifestations of Behçet’s disease, treatment responses, mortality, and morbidity. Behçet’s disease has been reported to be more prevalent in males from certain geographic regions and particular ethnic groups; however, recent reports indicate more even gender distribution across the world. There are gender differences in clinical manifestations and severity of the disease. Ocular manifestations, vascular involvement, and neurologic symptoms are more frequently reported in male patients whereas oral and genital ulcers, skin lesions, and arthritis occur more frequently in female patients. The disease can have a more severe course in males, and overall mortality rate is significantly higher among young male patients.http://dx.doi.org/10.1155/2014/820710 |
| spellingShingle | Didar Ucar-Comlekoglu Austin Fox H. Nida Sen Gender Differences in Behçet’s Disease Associated Uveitis Journal of Ophthalmology |
| title | Gender Differences in Behçet’s Disease Associated Uveitis |
| title_full | Gender Differences in Behçet’s Disease Associated Uveitis |
| title_fullStr | Gender Differences in Behçet’s Disease Associated Uveitis |
| title_full_unstemmed | Gender Differences in Behçet’s Disease Associated Uveitis |
| title_short | Gender Differences in Behçet’s Disease Associated Uveitis |
| title_sort | gender differences in behcet s disease associated uveitis |
| url | http://dx.doi.org/10.1155/2014/820710 |
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