Candidalysin biology and activation of host cells

Candidalysin biology and activation of host cells

ABSTRACT Candida albicans is an opportunistic fungal pathogen that can cause life-threatening systemic infections and distressing mucosal infections. A major breakthrough in understanding C. albicans pathogenicity was the discovery of candidalysin, the first cytolytic peptide toxin identified in a h...

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Bibliographic Details
Main Authors: Léa Lortal, Claire M. Lyon, Jakob L. Sprague, Johannes Sonnberger, Olivia K. A. Paulin, Don N. Wickramasinghe, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
Subjects:
Candida albicans
candidalysin
fungal infection
immune mechanisms
toxins
Online Access:https://journals.asm.org/doi/10.1128/mbio.00603-24
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