Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens
The objectives of this study were to investigate whether an increased dietary myo-inositol (MI) supply translates into changes in MI concentrations and endogenous mucosal phosphatase activities in the intestine of laying hens and whether different laying hen strains respond differently to MI supplem...
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Elsevier
2025-01-01
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| Series: | Poultry Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579124011234 |
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| author | Vera Sommerfeld Anna Hanauska Korinna Huber Jörn Bennewitz Amélia Camarinha-Silva Martina Feger Michael Föller Michael Oster Siriluck Ponsuksili Sonja Schmucker Jana Seifert Volker Stefanski Klaus Wimmers Markus Rodehutscord |
| author_facet | Vera Sommerfeld Anna Hanauska Korinna Huber Jörn Bennewitz Amélia Camarinha-Silva Martina Feger Michael Föller Michael Oster Siriluck Ponsuksili Sonja Schmucker Jana Seifert Volker Stefanski Klaus Wimmers Markus Rodehutscord |
| author_sort | Vera Sommerfeld |
| collection | DOAJ |
| description | The objectives of this study were to investigate whether an increased dietary myo-inositol (MI) supply translates into changes in MI concentrations and endogenous mucosal phosphatase activities in the intestine of laying hens and whether different laying hen strains respond differently to MI supplementation. The diets were corn–soybean meal-based and supplemented without (MI0) or with 1 (MI1), 2 (MI2), or 3 (MI3) g MI/kg feed. Ten hens per strain (Lohmann Brown-classic (LB) and Lohmann LSL-classic (LSL)) and diet were sacrificed at the age of 30 wk following a 4-wk stay in a metabolic unit. The blood plasma, digesta of the duodenum+jejunum and distal ileum, mucosa of the duodenum, and eggs were collected at wk 30. The concentration of MI in the blood plasma was increased by MI supplementation (P < 0.001); however, that of MI3 did not further increase compared with MI2. The concentration of MI in the duodenum+jejunum and ileum increased steadily (P < 0.001). The MI concentration in the duodenum+jejunum was higher in LB than in LSL hens (P = 0.017). The MI concentration in egg yolk was increased by MI supplementation (P < 0.001) and was higher in LB than in LSL hens (P = 0.015). Strain or diet did not affect mucosal phosphatase activity. Myo-inositol flow at the terminal ileum and postileal disappearance increased with each increment in MI supplementation (P < 0.001) and was higher in LB than in LSL hens (P ≤ 0.041). Regression analysis indicated that, on average, 84% of supplemented MI was retained in the body or metabolized and excreted in a different form. Based on the measured MI concentrations in the blood and eggs, dietary MI was not completely absorbed in the small intestine and, to a different extent, in the two laying hen strains. A higher dietary MI supply was followed by higher intestinal absorption or metabolism by microorganisms. The fate of supplemented MI and its relevance to birds warrant further research. |
| format | Article |
| id | doaj-art-0b5b43080a2c42d6b4ccc4644b389200 |
| institution | Kabale University |
| issn | 0032-5791 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
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| series | Poultry Science |
| spelling | doaj-art-0b5b43080a2c42d6b4ccc4644b3892002025-01-22T05:40:25ZengElsevierPoultry Science0032-57912025-01-011041104545Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hensVera Sommerfeld0Anna Hanauska1Korinna Huber2Jörn Bennewitz3Amélia Camarinha-Silva4Martina Feger5Michael Föller6Michael Oster7Siriluck Ponsuksili8Sonja Schmucker9Jana Seifert10Volker Stefanski11Klaus Wimmers12Markus Rodehutscord13Institute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyDepartment of Physiology, University of Hohenheim, 70599 Stuttgart, GermanyDepartment of Physiology, University of Hohenheim, 70599 Stuttgart, GermanyResearch Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, GermanyResearch Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, GermanyResearch Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, GermanyInstitute of Animal Science, University of Hohenheim, 70599 Stuttgart, Germany; Corresponding author at: Institut für Nutztierwissenschaften, Universität Hohenheim, 70599 Stuttgart, Germany.The objectives of this study were to investigate whether an increased dietary myo-inositol (MI) supply translates into changes in MI concentrations and endogenous mucosal phosphatase activities in the intestine of laying hens and whether different laying hen strains respond differently to MI supplementation. The diets were corn–soybean meal-based and supplemented without (MI0) or with 1 (MI1), 2 (MI2), or 3 (MI3) g MI/kg feed. Ten hens per strain (Lohmann Brown-classic (LB) and Lohmann LSL-classic (LSL)) and diet were sacrificed at the age of 30 wk following a 4-wk stay in a metabolic unit. The blood plasma, digesta of the duodenum+jejunum and distal ileum, mucosa of the duodenum, and eggs were collected at wk 30. The concentration of MI in the blood plasma was increased by MI supplementation (P < 0.001); however, that of MI3 did not further increase compared with MI2. The concentration of MI in the duodenum+jejunum and ileum increased steadily (P < 0.001). The MI concentration in the duodenum+jejunum was higher in LB than in LSL hens (P = 0.017). The MI concentration in egg yolk was increased by MI supplementation (P < 0.001) and was higher in LB than in LSL hens (P = 0.015). Strain or diet did not affect mucosal phosphatase activity. Myo-inositol flow at the terminal ileum and postileal disappearance increased with each increment in MI supplementation (P < 0.001) and was higher in LB than in LSL hens (P ≤ 0.041). Regression analysis indicated that, on average, 84% of supplemented MI was retained in the body or metabolized and excreted in a different form. Based on the measured MI concentrations in the blood and eggs, dietary MI was not completely absorbed in the small intestine and, to a different extent, in the two laying hen strains. A higher dietary MI supply was followed by higher intestinal absorption or metabolism by microorganisms. The fate of supplemented MI and its relevance to birds warrant further research.http://www.sciencedirect.com/science/article/pii/S0032579124011234EggLaying henMucosal phosphataseMyo-inositolPhosphorus |
| spellingShingle | Vera Sommerfeld Anna Hanauska Korinna Huber Jörn Bennewitz Amélia Camarinha-Silva Martina Feger Michael Föller Michael Oster Siriluck Ponsuksili Sonja Schmucker Jana Seifert Volker Stefanski Klaus Wimmers Markus Rodehutscord Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens Poultry Science Egg Laying hen Mucosal phosphatase Myo-inositol Phosphorus |
| title | Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens |
| title_full | Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens |
| title_fullStr | Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens |
| title_full_unstemmed | Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens |
| title_short | Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens |
| title_sort | effects of myo inositol supplementation in the diet on myo inositol concentrations in the intestine blood eggs and excreta of laying hens |
| topic | Egg Laying hen Mucosal phosphatase Myo-inositol Phosphorus |
| url | http://www.sciencedirect.com/science/article/pii/S0032579124011234 |
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