Sarcoidosis Presenting as Acute Respiratory Distress Syndrome
Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory cytokines. Acute pulmonary manifestations, esp...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/6465180 |
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| _version_ | 1832545968020520960 |
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| author | Bilal Haider Lashari Ahmad Raza Vincent Chan William Ward |
| author_facet | Bilal Haider Lashari Ahmad Raza Vincent Chan William Ward |
| author_sort | Bilal Haider Lashari |
| collection | DOAJ |
| description | Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory cytokines. Acute pulmonary manifestations, especially acute respiratory failure or acute respiratory distress syndrome, remain extremely uncommon in individuals without a prior diagnosis. We present the case of a 41-year-old African American female, who presented with ARDS. An extensive workup into the cause of her illness remained negative, and she subsequently succumbed to her illness. A diagnosis of sarcoidosis was made upon autopsy, after exclusion of other granulomatous illness. The case highlights the need to consider this uncommon diagnosis in patients with unexplained ARDS to guide therapy. |
| format | Article |
| id | doaj-art-0b40e8842ded470e8e321c27958d5ab6 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-0b40e8842ded470e8e321c27958d5ab62025-02-03T07:24:04ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/64651806465180Sarcoidosis Presenting as Acute Respiratory Distress SyndromeBilal Haider Lashari0Ahmad Raza1Vincent Chan2William Ward3Department of Internal Medicine, Abington Hospital–Jefferson Health, Abington, PA, USADepartment of Internal Medicine, Abington Hospital–Jefferson Health, Abington, PA, USADepartment of Internal Medicine, Abington Hospital–Jefferson Health, Abington, PA, USADepartment of Pulmonary and Critical Care Medicine–Jefferson Health, Abington, PA, USASarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory cytokines. Acute pulmonary manifestations, especially acute respiratory failure or acute respiratory distress syndrome, remain extremely uncommon in individuals without a prior diagnosis. We present the case of a 41-year-old African American female, who presented with ARDS. An extensive workup into the cause of her illness remained negative, and she subsequently succumbed to her illness. A diagnosis of sarcoidosis was made upon autopsy, after exclusion of other granulomatous illness. The case highlights the need to consider this uncommon diagnosis in patients with unexplained ARDS to guide therapy.http://dx.doi.org/10.1155/2018/6465180 |
| spellingShingle | Bilal Haider Lashari Ahmad Raza Vincent Chan William Ward Sarcoidosis Presenting as Acute Respiratory Distress Syndrome Case Reports in Medicine |
| title | Sarcoidosis Presenting as Acute Respiratory Distress Syndrome |
| title_full | Sarcoidosis Presenting as Acute Respiratory Distress Syndrome |
| title_fullStr | Sarcoidosis Presenting as Acute Respiratory Distress Syndrome |
| title_full_unstemmed | Sarcoidosis Presenting as Acute Respiratory Distress Syndrome |
| title_short | Sarcoidosis Presenting as Acute Respiratory Distress Syndrome |
| title_sort | sarcoidosis presenting as acute respiratory distress syndrome |
| url | http://dx.doi.org/10.1155/2018/6465180 |
| work_keys_str_mv | AT bilalhaiderlashari sarcoidosispresentingasacuterespiratorydistresssyndrome AT ahmadraza sarcoidosispresentingasacuterespiratorydistresssyndrome AT vincentchan sarcoidosispresentingasacuterespiratorydistresssyndrome AT williamward sarcoidosispresentingasacuterespiratorydistresssyndrome |