Sodium butyrate promotes synthesis of testosterone and meiosis of hyperuricemic male mice

Sodium butyrate promotes synthesis of testosterone and meiosis of hyperuricemic male mice

Abstract Hyperuricemia (HUA) impaires spermatogenesis. This study was carried out, aiming to determine whether butyric acid (NaB) avoids the HUA-induced decline of sperm quality HUA mice were developed through intra-peritoneal injection of the potassium oxalate combined with intragastric uric acid (...

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Bibliographic Details
Main Authors: Jiaojiao Qi, Yu Sun, Zeqing Chen, Ruipeng Gao, Miao Song, Tong Zou, Xuelin Gong, Shuang Wang, Qing Zhang, Chengyang Liu, Shichao Xing
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Hyperuricemia
Sodium butyrate
Sperm quality
Testosterone
Meiosis
Online Access:https://doi.org/10.1038/s41598-025-95846-6
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