Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features

Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features

BackgroundThe capability of mNGS in diagnosing suspected LRTIs and characterizing the respiratory microbiome in lung cancer patients requires further evaluation.MethodsThis study evaluated mNGS diagnostic performance and utilized background microbial sequences to characterize LRT microbiome in these...

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Bibliographic Details
Main Authors: Yao Liu, Bohan Yang, Qi Qi, Shijie Liu, Yiheng Du, Linlin Ye, Qiong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomic next-generation sequencing (mNGS)
lung cancer
lower respiratory tract infections (LRTIs)
microbiome
gene set variation analysis (GSVA)
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1518199/full
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