Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report
IntroductionClozapine and chlorpromazine are widely used for treating schizophrenia. However, irregular medical follow-ups are common in patients with schizophrenia, potentially leading to long-term super-dose medication. Managing such cases poses significant challenges for clinical psychiatrists.Ca...
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| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1533350/full |
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| author | Xiaobo Xie Jinzhang Chen Hongli Song Zebin Fan |
| author_facet | Xiaobo Xie Jinzhang Chen Hongli Song Zebin Fan |
| author_sort | Xiaobo Xie |
| collection | DOAJ |
| description | IntroductionClozapine and chlorpromazine are widely used for treating schizophrenia. However, irregular medical follow-ups are common in patients with schizophrenia, potentially leading to long-term super-dose medication. Managing such cases poses significant challenges for clinical psychiatrists.Case presentationThis report describes a 24-year-old Han Chinese male diagnosed with schizophrenia who had been taking long-term super-doses of clozapine (18–107 tablets/day, 25 mg/tablet) and chlorpromazine (7–40 tablets/day, 50 mg/tablet) for five months due to irregular medical follow-ups. Upon hospitalization, the doses of antipsychotic drugs were gradually tapered, and the medication regimen was adjusted based on the patient’s previous treatment history. Comprehensive health education about schizophrenia was also provided. The patient was followed for four years, during which his psychiatric symptoms remained under partial control.ConclusionClinicians must consider individual differences in the efficacy and adverse effects of antipsychotics and weigh the benefits and risks of combination therapy. Future efforts should focus on strengthening health education for patients with schizophrenia and their families to improve treatment compliance and outcomes. |
| format | Article |
| id | doaj-art-0b15a18fd3fd4f1e95434d243db45638 |
| institution | Kabale University |
| issn | 1664-0640 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj-art-0b15a18fd3fd4f1e95434d243db456382025-01-20T07:19:41ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-01-011510.3389/fpsyt.2024.15333501533350Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case reportXiaobo XieJinzhang ChenHongli SongZebin FanIntroductionClozapine and chlorpromazine are widely used for treating schizophrenia. However, irregular medical follow-ups are common in patients with schizophrenia, potentially leading to long-term super-dose medication. Managing such cases poses significant challenges for clinical psychiatrists.Case presentationThis report describes a 24-year-old Han Chinese male diagnosed with schizophrenia who had been taking long-term super-doses of clozapine (18–107 tablets/day, 25 mg/tablet) and chlorpromazine (7–40 tablets/day, 50 mg/tablet) for five months due to irregular medical follow-ups. Upon hospitalization, the doses of antipsychotic drugs were gradually tapered, and the medication regimen was adjusted based on the patient’s previous treatment history. Comprehensive health education about schizophrenia was also provided. The patient was followed for four years, during which his psychiatric symptoms remained under partial control.ConclusionClinicians must consider individual differences in the efficacy and adverse effects of antipsychotics and weigh the benefits and risks of combination therapy. Future efforts should focus on strengthening health education for patients with schizophrenia and their families to improve treatment compliance and outcomes.https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1533350/fullclozapinechlorpromazineantipsychoticsschizophreniacase report |
| spellingShingle | Xiaobo Xie Jinzhang Chen Hongli Song Zebin Fan Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report Frontiers in Psychiatry clozapine chlorpromazine antipsychotics schizophrenia case report |
| title | Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report |
| title_full | Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report |
| title_fullStr | Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report |
| title_full_unstemmed | Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report |
| title_short | Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report |
| title_sort | treatment of a schizophrenia patient on long term super dose antipsychotics a case report |
| topic | clozapine chlorpromazine antipsychotics schizophrenia case report |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1533350/full |
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