A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse

Although nitrous oxide (N2O) has long been used as an anesthetic, it’s use as a recreational drug has recently increased. As N2O abuse is associated with a number of adverse health effects, it has become a significant public health issue. Chronic abuse can lead to a number of neurological complicati...

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Main Authors: J. Guk, J. Valančienė, A. Klimašauskienė
Format: Article
Language:English
Published: Vilnius University Press 2024-02-01
Series:Neurologijos seminarai
Subjects:
Online Access:https://www.journals.vu.lt/neurologijos_seminarai/article/view/34586
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author J. Guk
J. Valančienė
A. Klimašauskienė
author_facet J. Guk
J. Valančienė
A. Klimašauskienė
author_sort J. Guk
collection DOAJ
description Although nitrous oxide (N2O) has long been used as an anesthetic, it’s use as a recreational drug has recently increased. As N2O abuse is associated with a number of adverse health effects, it has become a significant public health issue. Chronic abuse can lead to a number of neurological complications, most commonly related to functional vitamin B12 deficiency. One of the most encountered forms of N2O neurotoxicity is a subacute combined degeneration, which can cause permanent neurological damage. The medical community should therefore be aware of the increasing scale of recreational N2O exposure and the possible complications of this drug abuse. Early recognition and treatment of N2O toxicity are crucial. We present the case of an 18-year-old male who was diagnosed with subacute combined spinal cord degeneration related to N2O abuse.
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publishDate 2024-02-01
publisher Vilnius University Press
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series Neurologijos seminarai
spelling doaj-art-0afba67d604840adbd790b03e42e45ab2025-01-20T18:21:56ZengVilnius University PressNeurologijos seminarai1392-30642424-59172024-02-0127No. 2 (96)10.29014/NS.2023.27.14A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) AbuseJ. Guk0J. Valančienė1A. Klimašauskienė2Vilnius University, LithuaniaVilnius University, LithuaniaVilnius University, LithuaniaAlthough nitrous oxide (N2O) has long been used as an anesthetic, it’s use as a recreational drug has recently increased. As N2O abuse is associated with a number of adverse health effects, it has become a significant public health issue. Chronic abuse can lead to a number of neurological complications, most commonly related to functional vitamin B12 deficiency. One of the most encountered forms of N2O neurotoxicity is a subacute combined degeneration, which can cause permanent neurological damage. The medical community should therefore be aware of the increasing scale of recreational N2O exposure and the possible complications of this drug abuse. Early recognition and treatment of N2O toxicity are crucial. We present the case of an 18-year-old male who was diagnosed with subacute combined spinal cord degeneration related to N2O abuse. https://www.journals.vu.lt/neurologijos_seminarai/article/view/34586nitrous oxideN2O, neurotoxicityvitamin B12 deficiencysubacute combined degeneration
spellingShingle J. Guk
J. Valančienė
A. Klimašauskienė
A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse
Neurologijos seminarai
nitrous oxide
N2O, neurotoxicity
vitamin B12 deficiency
subacute combined degeneration
title A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse
title_full A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse
title_fullStr A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse
title_full_unstemmed A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse
title_short A Case Report of Subacute Combined Spinal Cord Degeneration Caused by Nitrous Oxide (‘Laughing Gas’) Abuse
title_sort case report of subacute combined spinal cord degeneration caused by nitrous oxide laughing gas abuse
topic nitrous oxide
N2O, neurotoxicity
vitamin B12 deficiency
subacute combined degeneration
url https://www.journals.vu.lt/neurologijos_seminarai/article/view/34586
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