An extension of Gompertzian growth dynamics: Weibull and Fréchet models

In this work a new probabilistic and dynamical approach to an extension of the Gompertz law is proposed. A generalized family of probability density functions, designated by $Beta^*(p,q)$, which is proportional to the right hand side of the Tsoularis-Wallace model, is studied. In particular, for $p...

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Main Authors: J. Leonel Rocha, Sandra M. Aleixo
Format: Article
Language:English
Published: AIMS Press 2012-12-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.379
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author J. Leonel Rocha
Sandra M. Aleixo
author_facet J. Leonel Rocha
Sandra M. Aleixo
author_sort J. Leonel Rocha
collection DOAJ
description In this work a new probabilistic and dynamical approach to an extension of the Gompertz law is proposed. A generalized family of probability density functions, designated by $Beta^*(p,q)$, which is proportional to the right hand side of the Tsoularis-Wallace model, is studied. In particular, for $p = 2$, the investigation is extended to the extreme value models of Weibull and Fréchet type. These models, described by differential equations, are proportional to the hyper-Gompertz growth model. It is proved that the $Beta^*(2,q)$ densities are a power of betas mixture, and that its dynamics are determined by a non-linear coupling of probabilities. The dynamical analysis is performed using techniques of symbolic dynamics and the system complexity is measured using topological entropy. Generally, the natural history of a malignant tumour is reflected through bifurcation diagrams, in which are identified regions of regression, stability, bifurcation, chaos and terminus.
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spelling doaj-art-0ae9f28a8ecb4ef287f64c498b5c1b082025-01-24T02:25:53ZengAIMS PressMathematical Biosciences and Engineering1551-00182012-12-0110237939810.3934/mbe.2013.10.379An extension of Gompertzian growth dynamics: Weibull and Fréchet modelsJ. Leonel Rocha0Sandra M. Aleixo1Instituto Superior de Engenharia de Lisboa - ISEL, ADM and CEAUL, Rua Conselheiro Emídio Navarro, 1, 1959-007 LisboaInstituto Superior de Engenharia de Lisboa - ISEL, ADM and CEAUL, Rua Conselheiro Emídio Navarro, 1, 1959-007 LisboaIn this work a new probabilistic and dynamical approach to an extension of the Gompertz law is proposed. A generalized family of probability density functions, designated by $Beta^*(p,q)$, which is proportional to the right hand side of the Tsoularis-Wallace model, is studied. In particular, for $p = 2$, the investigation is extended to the extreme value models of Weibull and Fréchet type. These models, described by differential equations, are proportional to the hyper-Gompertz growth model. It is proved that the $Beta^*(2,q)$ densities are a power of betas mixture, and that its dynamics are determined by a non-linear coupling of probabilities. The dynamical analysis is performed using techniques of symbolic dynamics and the system complexity is measured using topological entropy. Generally, the natural history of a malignant tumour is reflected through bifurcation diagrams, in which are identified regions of regression, stability, bifurcation, chaos and terminus.https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.379symbolic dynamicsq)$ densitiestumour dynamics.$beta^*(pbifurcations and chaostopological entropyextreme value lawsgrowth models
spellingShingle J. Leonel Rocha
Sandra M. Aleixo
An extension of Gompertzian growth dynamics: Weibull and Fréchet models
Mathematical Biosciences and Engineering
symbolic dynamics
q)$ densities
tumour dynamics.
$beta^*(p
bifurcations and chaos
topological entropy
extreme value laws
growth models
title An extension of Gompertzian growth dynamics: Weibull and Fréchet models
title_full An extension of Gompertzian growth dynamics: Weibull and Fréchet models
title_fullStr An extension of Gompertzian growth dynamics: Weibull and Fréchet models
title_full_unstemmed An extension of Gompertzian growth dynamics: Weibull and Fréchet models
title_short An extension of Gompertzian growth dynamics: Weibull and Fréchet models
title_sort extension of gompertzian growth dynamics weibull and frechet models
topic symbolic dynamics
q)$ densities
tumour dynamics.
$beta^*(p
bifurcations and chaos
topological entropy
extreme value laws
growth models
url https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.379
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