A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications
The importance of nanocomposites constantly attains attention because of their unique properties all across the fields especially in medical perspectives. The study of green-synthesized nanocomposites has grown to be extremely fascinating in the field of research. Nanocomposites are more promising t...
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| Language: | English |
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Elsevier
2025-02-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025000349 |
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| author | Mahnoor Khafsa Malik Abeer Kazmi Tahira Sultana Naveed Iqbal Raja Yamin Bibi Mazhar Abbas Irfan Anjum Badruddin M. Mahmood Ali Muhammad Nasir Bashir |
| author_facet | Mahnoor Khafsa Malik Abeer Kazmi Tahira Sultana Naveed Iqbal Raja Yamin Bibi Mazhar Abbas Irfan Anjum Badruddin M. Mahmood Ali Muhammad Nasir Bashir |
| author_sort | Mahnoor |
| collection | DOAJ |
| description | The importance of nanocomposites constantly attains attention because of their unique properties all across the fields especially in medical perspectives. The study of green-synthesized nanocomposites has grown to be extremely fascinating in the field of research. Nanocomposites are more promising than mono-metallic nanoparticles because they exhibit synergistic effects. This review encapsulates the current development in the formulation of plant-mediated nanocomposites by using several plant species and the impact of secondary metabolites on their biocompatible functioning. Phyto-synthesis produces diverse nanomaterials with biocompatibility, environment-friendliness, and in vivo actions, characterized by varying sizes, shapes, and biochemical nature. This process is advantageous to conventional physical and chemical procedures. New studies have been conducted to determine the biomedical efficacy of nanocomposites against various diseases. Unfortunately, there has been inadequate investigation into green-assisted nanocomposites. Incorporating phytosynthesized nanocomposites in therapeutic interventions not only enhances healing processes but also augments the host's immune defenses against infections. This review highlights the phytosynthesis of nanocomposites and their various biomedical applications, including antibacterial, antidiabetic, antiviral, antioxidant, antifungal, anti-cancer, and other applications, as well as their toxicity. This review also explores the mechanistic action of nanocomposites to achieve their designated tasks. Biogenic nanocomposites for multimodal imaging have the potential to exchange the conventional methods and materials in biomedical research. Well-designed nanocomposites have the potential to be utilized in various biomedical fields as innovative theranostic agents with the subsequent objective of efficiently diagnosing and treating a variety of human disorders. |
| format | Article |
| id | doaj-art-0ae8357e754240d3bea5bbf6a5a023c4 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-0ae8357e754240d3bea5bbf6a5a023c42025-01-26T05:04:13ZengElsevierHeliyon2405-84402025-02-01113e41654A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications Mahnoor0Khafsa Malik1Abeer Kazmi2Tahira Sultana3Naveed Iqbal Raja4Yamin Bibi5Mazhar Abbas6Irfan Anjum Badruddin7M. Mahmood Ali8Muhammad Nasir Bashir9Department of Botany, PMAS, Arid Agriculture University Rawalpindi, PakistanDepartment of Botany, PMAS, Arid Agriculture University Rawalpindi, Pakistan; Corresponding author.The State Key Laboratory of Freshwater Ecology and Biotechnology, The Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, Hubei, PR China; University of Chinese Academy of Sciences, Beijing, 100049, PR ChinaDepartment of Botany, PMAS, Arid Agriculture University Rawalpindi, Pakistan; Corresponding author.Department of Botany, PMAS, Arid Agriculture University Rawalpindi, PakistanDepartment of Botany, Rawalpindi Women University, Rawalpindi, PakistanDepartment of Biochemistry, University of Veterinary and Animal Science Lahore (Jhang Campus), Jhang, 35200, PakistanMechanical Engineering Department, College of Engineering, King Khalid University, Abha, 61421, Saudi ArabiaDepartment of Mechatronic Engineering, Atlantic Technological University Sligo, Ash Lane, F91 YW50, Sligo, IrelandDepartment of Mechanical Engineering, Yonsei University, Seoul, 120-749, Republic of KoreaThe importance of nanocomposites constantly attains attention because of their unique properties all across the fields especially in medical perspectives. The study of green-synthesized nanocomposites has grown to be extremely fascinating in the field of research. Nanocomposites are more promising than mono-metallic nanoparticles because they exhibit synergistic effects. This review encapsulates the current development in the formulation of plant-mediated nanocomposites by using several plant species and the impact of secondary metabolites on their biocompatible functioning. Phyto-synthesis produces diverse nanomaterials with biocompatibility, environment-friendliness, and in vivo actions, characterized by varying sizes, shapes, and biochemical nature. This process is advantageous to conventional physical and chemical procedures. New studies have been conducted to determine the biomedical efficacy of nanocomposites against various diseases. Unfortunately, there has been inadequate investigation into green-assisted nanocomposites. Incorporating phytosynthesized nanocomposites in therapeutic interventions not only enhances healing processes but also augments the host's immune defenses against infections. This review highlights the phytosynthesis of nanocomposites and their various biomedical applications, including antibacterial, antidiabetic, antiviral, antioxidant, antifungal, anti-cancer, and other applications, as well as their toxicity. This review also explores the mechanistic action of nanocomposites to achieve their designated tasks. Biogenic nanocomposites for multimodal imaging have the potential to exchange the conventional methods and materials in biomedical research. Well-designed nanocomposites have the potential to be utilized in various biomedical fields as innovative theranostic agents with the subsequent objective of efficiently diagnosing and treating a variety of human disorders.http://www.sciencedirect.com/science/article/pii/S2405844025000349NanocompositesGreen synthesisBiomedical applicationsToxicity |
| spellingShingle | Mahnoor Khafsa Malik Abeer Kazmi Tahira Sultana Naveed Iqbal Raja Yamin Bibi Mazhar Abbas Irfan Anjum Badruddin M. Mahmood Ali Muhammad Nasir Bashir A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications Heliyon Nanocomposites Green synthesis Biomedical applications Toxicity |
| title | A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications |
| title_full | A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications |
| title_fullStr | A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications |
| title_full_unstemmed | A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications |
| title_short | A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications |
| title_sort | mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications |
| topic | Nanocomposites Green synthesis Biomedical applications Toxicity |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025000349 |
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