Occupational Exposures and Chronic Airflow Limitation

The recent literature was reviewed to evaluate whether chronic airflow limitation is associated with occupational exposures to dusts. Only those studies that controlled for the effects of smoking were included. There is compelling evidence that exposure to inorganic dusts, such as from coal and hard...

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Main Authors: Helen Dimich-Ward, Susan M Kennedy, Moira Chan-Yeung
Format: Article
Language:English
Published: Wiley 1996-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1996/146138
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author Helen Dimich-Ward
Susan M Kennedy
Moira Chan-Yeung
author_facet Helen Dimich-Ward
Susan M Kennedy
Moira Chan-Yeung
author_sort Helen Dimich-Ward
collection DOAJ
description The recent literature was reviewed to evaluate whether chronic airflow limitation is associated with occupational exposures to dusts. Only those studies that controlled for the effects of smoking were included. There is compelling evidence that exposure to inorganic dusts, such as from coal and hardrock mining or asbestos, are associated with the development of chronic airflow limitation, independently of pneumoconiosis. Nonsmoking gold miners are particularly at high risk of airflow obstruction and emphysema. Findings from studies of organic dusts, such as exposures to wood, cotton, grain or other agricultural dusts, or to mixed dust exposures, were less consistent but tended to show positive dose-response associations. In the majority of studies, no statistical interaction was shown between dust exposures and smoking; however, the effects of the dust exposures were often more pronounced. An occupational history should be considered, in addition to a smoking history, as an integral part of an investigation of chronic airflow limitation in a patient.
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spelling doaj-art-0ade9e5bcef14c45b820dce5a382dbd02025-02-03T01:26:36ZengWileyCanadian Respiratory Journal1198-22411996-01-013213314010.1155/1996/146138Occupational Exposures and Chronic Airflow LimitationHelen Dimich-WardSusan M KennedyMoira Chan-YeungThe recent literature was reviewed to evaluate whether chronic airflow limitation is associated with occupational exposures to dusts. Only those studies that controlled for the effects of smoking were included. There is compelling evidence that exposure to inorganic dusts, such as from coal and hardrock mining or asbestos, are associated with the development of chronic airflow limitation, independently of pneumoconiosis. Nonsmoking gold miners are particularly at high risk of airflow obstruction and emphysema. Findings from studies of organic dusts, such as exposures to wood, cotton, grain or other agricultural dusts, or to mixed dust exposures, were less consistent but tended to show positive dose-response associations. In the majority of studies, no statistical interaction was shown between dust exposures and smoking; however, the effects of the dust exposures were often more pronounced. An occupational history should be considered, in addition to a smoking history, as an integral part of an investigation of chronic airflow limitation in a patient.http://dx.doi.org/10.1155/1996/146138
spellingShingle Helen Dimich-Ward
Susan M Kennedy
Moira Chan-Yeung
Occupational Exposures and Chronic Airflow Limitation
Canadian Respiratory Journal
title Occupational Exposures and Chronic Airflow Limitation
title_full Occupational Exposures and Chronic Airflow Limitation
title_fullStr Occupational Exposures and Chronic Airflow Limitation
title_full_unstemmed Occupational Exposures and Chronic Airflow Limitation
title_short Occupational Exposures and Chronic Airflow Limitation
title_sort occupational exposures and chronic airflow limitation
url http://dx.doi.org/10.1155/1996/146138
work_keys_str_mv AT helendimichward occupationalexposuresandchronicairflowlimitation
AT susanmkennedy occupationalexposuresandchronicairflowlimitation
AT moirachanyeung occupationalexposuresandchronicairflowlimitation