A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements

Acute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and...

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Main Authors: Stephanie M. Toth-Manikowski, Hanni Menn-Josephy, Jasvinder Bhatia
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2014/128145
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author Stephanie M. Toth-Manikowski
Hanni Menn-Josephy
Jasvinder Bhatia
author_facet Stephanie M. Toth-Manikowski
Hanni Menn-Josephy
Jasvinder Bhatia
author_sort Stephanie M. Toth-Manikowski
collection DOAJ
description Acute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and without the classic metabolic derangements. We present a case of chronic ethylene glycol ingestion in a patient who presented with acute kidney injury and repeated denials of an exposure history. Kidney biopsy was critical to the elucidation of the cause of his worsening renal function.
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institution Kabale University
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series Case Reports in Nephrology
spelling doaj-art-0ac56f88a22447339517e8ef0dc7812b2025-02-03T06:08:16ZengWileyCase Reports in Nephrology2090-66412090-665X2014-01-01201410.1155/2014/128145128145A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic DerangementsStephanie M. Toth-Manikowski0Hanni Menn-Josephy1Jasvinder Bhatia2Department of Medicine, Boston Medical Center, 72 East Concord Street, Evans 124, Boston, MA 02118, USARenal Section, Boston University School of Medicine, 650 Albany Street, Rm 504, Boston, MA 02118, USARenal Section, Boston University School of Medicine, 650 Albany Street, Rm 504, Boston, MA 02118, USAAcute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and without the classic metabolic derangements. We present a case of chronic ethylene glycol ingestion in a patient who presented with acute kidney injury and repeated denials of an exposure history. Kidney biopsy was critical to the elucidation of the cause of his worsening renal function.http://dx.doi.org/10.1155/2014/128145
spellingShingle Stephanie M. Toth-Manikowski
Hanni Menn-Josephy
Jasvinder Bhatia
A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
Case Reports in Nephrology
title A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_full A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_fullStr A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_full_unstemmed A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_short A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_sort case of chronic ethylene glycol intoxication presenting without classic metabolic derangements
url http://dx.doi.org/10.1155/2014/128145
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