Interleukin-1 signaling and CD4+ T cells control B cell recruitment to the lungs in chronic beryllium disease

Interleukin-1 signaling and CD4+ T cells control B cell recruitment to the lungs in chronic beryllium disease

Chronic beryllium disease (CBD) is a debilitating pulmonary disorder that occurs due to persistent exposure to beryllium (Be) particles in the workplace. Be-exposure causes activation of the innate immune system, resulting in the secretion of interleukins and chemokines that drive the accumulation o...

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Bibliographic Details
Main Authors: Joseph M. Gaballa, Caley Valdez, Douglas G. Mack, Faiz Minhajuddin, Masoom Raza, Tabrez A. Mohammad, Allison K. Martin, Andrew Getahun, Charles A. Dinarello, Andrew P. Fontenot, Shaikh M. Atif
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
interleukins
IL-1
IL-1Ra
Anakinra
chemokines
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1479348/full
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