A novel uORF regulates folliculin to promote cell growth and lysosomal biogenesis during cardiac stress
Abstract Pathological cardiac remodeling is a maladaptive response that leads to changes in the size, structure, and function of the heart. These changes occur due to an acute or chronic stress on the heart and involve a complex interplay of hemodynamic, neurohormonal and molecular factors. As a cri...
Saved in:
Main Authors: | Maja Bencun, Laura Spreyer, Etienne Boileau, Jessica Eschenbach, Norbert Frey, Christoph Dieterich, Mirko Völkers |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-87107-3 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis
by: Jinwang Ye, et al.
Published: (2025-01-01) -
Research Progress on Metabolic Regulation of Lysosomes and Their Regulatory Mechanism on Meat Tenderness
by: DONG Yushan, DU Rui, SU Rina, YAO Lili, DU Xuerong, LI Chenlong, WU Junqin, HOU Yanru, LUO Yulong
Published: (2025-02-01) -
Autophagy-lysosome pathway in insulin & glucagon homeostasis
by: Yi Wu, et al.
Published: (2025-02-01) -
Local wisdom tradition of maintenance of the upstream river
by: Ine Kusuma Aryani, et al.
Published: (2024-06-01) -
Non-Canonical, Extralysosomal Activities of Lysosomal Peptidases in Physiological and Pathological Conditions: New Clinical Opportunities for Cancer Therapy
by: Ryan Conesa-Bakkali, et al.
Published: (2025-01-01)