What is the optimal biological therapy for moderate to severe ulcerative colitis: a systematic review and network meta-analysis

What is the optimal biological therapy for moderate to severe ulcerative colitis: a systematic review and network meta-analysis

ObjectiveThe biologics for moderate to severe ulcerative colitis (UC) have expanded with an increasing array. We performed an updated network meta-analysis to evaluate and compare the relative efficacy and safety profiles of biologics in moderate to severe UC.DesignWe searched literature to 18 May 2...

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Bibliographic Details
Main Authors: Longbin Huang, Chen Kong, Ningning Yue, Hailan Zhao, Yuan Zhang, Chengmei Tian, Zhiliang Mai, Daoru Wei, Ruiyue Shi, Jun Yao, Lisheng Wang, Defeng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
biological therapy
clinical trials
bayesian network meta-analysis
systematic review
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1602024/full
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