Strategies in the Surgical Management of Atrial Fibrillation
Atrial fibrillation (AF) is associated with substantial morbidity, mortality, and economic burden and confers a lifetime risk of up to 25%. Current medical management involves thromboembolism prevention, rate, and rhythm control. An increased understanding of AF pathophysiology has led to enhanced p...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.4061/2011/439312 |
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| _version_ | 1832550673275682816 |
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| author | Leanne Harling Thanos Athanasiou Hutan Ashrafian Justin Nowell Antonios Kourliouros |
| author_facet | Leanne Harling Thanos Athanasiou Hutan Ashrafian Justin Nowell Antonios Kourliouros |
| author_sort | Leanne Harling |
| collection | DOAJ |
| description | Atrial fibrillation (AF) is associated with substantial morbidity, mortality, and economic burden and confers a lifetime risk of up to 25%. Current medical management involves thromboembolism prevention, rate, and rhythm control. An increased understanding of AF pathophysiology has led to enhanced pharmacological and medical therapies; however this is often limited by toxicity, variable symptom control, and inability to modulate the atrial substrate. Surgical AF ablation has been available since the original description of the Cox Maze procedure, either as a standalone or concomitant intervention. Advances in novel energy delivery systems have allowed the development of less technically demanding procedures potentially eliminating the need for median sternotomy and cardiopulmonary bypass. Variations in the definition, duration, and reporting of AF have produced methodological limitations impacting on the validity of interstudy comparisons. Standardization of these parameters may, in future, allow us to further evaluate clinical endpoints and establish the efficacy of these techniques. |
| format | Article |
| id | doaj-art-0a9ec6ec22e1487c84747fd7b361ac50 |
| institution | Kabale University |
| issn | 2090-0597 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-0a9ec6ec22e1487c84747fd7b361ac502025-02-03T06:06:00ZengWileyCardiology Research and Practice2090-05972011-01-01201110.4061/2011/439312439312Strategies in the Surgical Management of Atrial FibrillationLeanne Harling0Thanos Athanasiou1Hutan Ashrafian2Justin Nowell3Antonios Kourliouros4Department of Surgery and Cancer, Imperial College London, London, W2 1NY, UKDepartment of Surgery and Cancer, Imperial College London, London, W2 1NY, UKDepartment of Surgery and Cancer, Imperial College London, London, W2 1NY, UKDepartment of Surgery and Cancer, Imperial College London, London, W2 1NY, UKDepartment of Surgery and Cancer, Imperial College London, London, W2 1NY, UKAtrial fibrillation (AF) is associated with substantial morbidity, mortality, and economic burden and confers a lifetime risk of up to 25%. Current medical management involves thromboembolism prevention, rate, and rhythm control. An increased understanding of AF pathophysiology has led to enhanced pharmacological and medical therapies; however this is often limited by toxicity, variable symptom control, and inability to modulate the atrial substrate. Surgical AF ablation has been available since the original description of the Cox Maze procedure, either as a standalone or concomitant intervention. Advances in novel energy delivery systems have allowed the development of less technically demanding procedures potentially eliminating the need for median sternotomy and cardiopulmonary bypass. Variations in the definition, duration, and reporting of AF have produced methodological limitations impacting on the validity of interstudy comparisons. Standardization of these parameters may, in future, allow us to further evaluate clinical endpoints and establish the efficacy of these techniques.http://dx.doi.org/10.4061/2011/439312 |
| spellingShingle | Leanne Harling Thanos Athanasiou Hutan Ashrafian Justin Nowell Antonios Kourliouros Strategies in the Surgical Management of Atrial Fibrillation Cardiology Research and Practice |
| title | Strategies in the Surgical Management of Atrial Fibrillation |
| title_full | Strategies in the Surgical Management of Atrial Fibrillation |
| title_fullStr | Strategies in the Surgical Management of Atrial Fibrillation |
| title_full_unstemmed | Strategies in the Surgical Management of Atrial Fibrillation |
| title_short | Strategies in the Surgical Management of Atrial Fibrillation |
| title_sort | strategies in the surgical management of atrial fibrillation |
| url | http://dx.doi.org/10.4061/2011/439312 |
| work_keys_str_mv | AT leanneharling strategiesinthesurgicalmanagementofatrialfibrillation AT thanosathanasiou strategiesinthesurgicalmanagementofatrialfibrillation AT hutanashrafian strategiesinthesurgicalmanagementofatrialfibrillation AT justinnowell strategiesinthesurgicalmanagementofatrialfibrillation AT antonioskourliouros strategiesinthesurgicalmanagementofatrialfibrillation |