Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world

The chemotherapy results have been analyzed in tuberculosis patients suffering from multiple drug resistance registered for treatment in the Russian Federation in 2011-2012 compared with the treatment outcomes of MDR patients registered for treatment in the world, BRICS and countries of the former S...

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Main Authors: S. A. Sterlikov, V. V. Testov, I. A. Vasilieva
Format: Article
Language:Russian
Published: New Terra Publishing House 2016-01-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/838
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author S. A. Sterlikov
V. V. Testov
I. A. Vasilieva
author_facet S. A. Sterlikov
V. V. Testov
I. A. Vasilieva
author_sort S. A. Sterlikov
collection DOAJ
description The chemotherapy results have been analyzed in tuberculosis patients suffering from multiple drug resistance registered for treatment in the Russian Federation in 2011-2012 compared with the treatment outcomes of MDR patients registered for treatment in the world, BRICS and countries of the former Soviet Union in 2011. Treatment outcomes of XDR TB patients have been analyzed for the first time. Chemotherapy efficiency in MDR TB patients in the Russian Federation in the cohort of 2011 made 37.1%, and in the cohort of 2012 made 39.1%, which significantly lower than in the world in general (47.5%), in BRICS and countries of the former Soviet Union; this low treatment efficiency is mostly due to treatment failures (18.3%) and those died (19.1%). The treatment efficiency of XDR TB patients registered for treatment in the Russian Federation in 2012 made 26.2% versus 22.0% in the cohort of 2011. Considering the significant financial costs spent on the treatment, the chemotherapy efficiency of M/XDR TB patients in the Russian Federation is too low to improve the epidemic situation and some additional measures are to be taken for its improvement.
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institution OA Journals
issn 2075-1230
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series Туберкулез и болезни лёгких
spelling doaj-art-0a9a72c5c3394e4492fbecc49f368ebc2025-08-20T02:05:56ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062016-01-019412227838Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the worldS. A. Sterlikov0V. V. Testov1I. A. Vasilieva2M. I. Sechenov First Moscow State Medical UniversityCentral Tuberculosis Research InstituteCentral Tuberculosis Research InstituteThe chemotherapy results have been analyzed in tuberculosis patients suffering from multiple drug resistance registered for treatment in the Russian Federation in 2011-2012 compared with the treatment outcomes of MDR patients registered for treatment in the world, BRICS and countries of the former Soviet Union in 2011. Treatment outcomes of XDR TB patients have been analyzed for the first time. Chemotherapy efficiency in MDR TB patients in the Russian Federation in the cohort of 2011 made 37.1%, and in the cohort of 2012 made 39.1%, which significantly lower than in the world in general (47.5%), in BRICS and countries of the former Soviet Union; this low treatment efficiency is mostly due to treatment failures (18.3%) and those died (19.1%). The treatment efficiency of XDR TB patients registered for treatment in the Russian Federation in 2012 made 26.2% versus 22.0% in the cohort of 2011. Considering the significant financial costs spent on the treatment, the chemotherapy efficiency of M/XDR TB patients in the Russian Federation is too low to improve the epidemic situation and some additional measures are to be taken for its improvement.https://www.tibl-journal.com/jour/article/view/838multiple drug resistant tuberculosistreatment outcomes in mdr tb patientstreatment outcomes in xdr tb patientselimination of mdr tb pool of infection
spellingShingle S. A. Sterlikov
V. V. Testov
I. A. Vasilieva
Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
Туберкулез и болезни лёгких
multiple drug resistant tuberculosis
treatment outcomes in mdr tb patients
treatment outcomes in xdr tb patients
elimination of mdr tb pool of infection
title Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
title_full Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
title_fullStr Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
title_full_unstemmed Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
title_short Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
title_sort treatment results of patients with multiple and extensive drug resistance registered in 2012 in the russian federation and in the world
topic multiple drug resistant tuberculosis
treatment outcomes in mdr tb patients
treatment outcomes in xdr tb patients
elimination of mdr tb pool of infection
url https://www.tibl-journal.com/jour/article/view/838
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AT vvtestov treatmentresultsofpatientswithmultipleandextensivedrugresistanceregisteredin2012intherussianfederationandintheworld
AT iavasilieva treatmentresultsofpatientswithmultipleandextensivedrugresistanceregisteredin2012intherussianfederationandintheworld