Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, followed by an intestinal perforation: a case report

Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, followed by an intestinal perforation: a case report

Abstract Background Mantle cell lymphoma is a diverse B-cell lymphoma with varying clinical behaviors. Treating relapsed or refractory mantle cell lymphoma is challenging, with Bruton’s tyrosine kinase inhibitors proving effective but not curative. Post-Bruton’s tyrosine kinase inhibitor failure, th...

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Bibliographic Details
Main Authors: G. Menardi, A. Castellino, C. Castellino, M. E. Bersia, E. Grande, G. Fraternali, M. Massaia, C. Fruttero
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Medical Case Reports
Subjects:
CAR-T therapy
Mantle cell lymphoma
Immune effector cell-associated hematotoxicity
Cytokine release syndrome
Immune effector cell-associated neurotoxicity syndrome
Adverse drug reaction
Online Access:https://doi.org/10.1186/s13256-024-04905-5
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