Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial
Abstract Background Poor quality of life in adults with anorexia nervosa (AN) and persistent high rates of readmission highlight the necessity of developing interventions to optimize treatment outcomes. ECHOMANTRA is a novel online intervention based on interventions for carers (Experienced Carers H...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
|
| Series: | Journal of Eating Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40337-024-01166-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832595021571817472 |
|---|---|
| author | Yolanda Quiles Álvaro Ruiz Eva León-Zarceño Javier Manchón Marie-Carmen Neipp Sofía Payá-López Katina Kovacheva Valentina Cardi |
| author_facet | Yolanda Quiles Álvaro Ruiz Eva León-Zarceño Javier Manchón Marie-Carmen Neipp Sofía Payá-López Katina Kovacheva Valentina Cardi |
| author_sort | Yolanda Quiles |
| collection | DOAJ |
| description | Abstract Background Poor quality of life in adults with anorexia nervosa (AN) and persistent high rates of readmission highlight the necessity of developing interventions to optimize treatment outcomes. ECHOMANTRA is a novel online intervention based on interventions for carers (Experienced Carers Helping Others, ECHO) and patients (Maudsley Model of Anorexia Nervosa Treatment for Adults, MANTRA) with anorexia nervosa. The objective of this paper is to describe the study protocol of a randomized control trial (RCT) aimed at evaluating the efficacy of an adaptation of the ECHOMANTRA for adults AN inpatients and outpatients, and their carers, to be implemented as an add-on to treatment-as-usual (TAU). Methods In a multi − center pilot randomized controlled trial (RCT), 148 adult AN patients, and their carers, will be randomized to receive treatment as usual (TAU) or TAU plus ECHOMANTRA. Assessments will take place at baseline (T0), post-intervention (2-month) (T1), 6-month follow-up (T2), and 12-month follow-up (T3). Primary outcomes will be eating disorder psychopathology and psychological well-being. For carers, outcome variables will include psychological well-being, accommodation and enabling behaviors, expressed emotion, illness burden, quality of life and care skills. Discussion This study will provide evidence of the efficacy of this novel, online and protocolized intervention in facilitating the recovery of these patients. Trial registration ISRCTN registry (Identifier: 80253157 https://doi.org/10.1186/ISRCTN80253157 ). |
| format | Article |
| id | doaj-art-0a603a4e60274bad89b7403c53b662b0 |
| institution | Kabale University |
| issn | 2050-2974 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Eating Disorders |
| spelling | doaj-art-0a603a4e60274bad89b7403c53b662b02025-01-19T12:04:23ZengBMCJournal of Eating Disorders2050-29742025-01-0113111110.1186/s40337-024-01166-xEfficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trialYolanda Quiles0Álvaro Ruiz1Eva León-Zarceño2Javier Manchón3Marie-Carmen Neipp4Sofía Payá-López5Katina Kovacheva6Valentina Cardi7Department of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández UniversityDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández UniversityDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández UniversityDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández UniversityDepartment of Health Psychology, Miguel Hernández UniversityDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández UniversityDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández UniversityDipartamento di Psicologia Generale, Università degli Studi di PadovaAbstract Background Poor quality of life in adults with anorexia nervosa (AN) and persistent high rates of readmission highlight the necessity of developing interventions to optimize treatment outcomes. ECHOMANTRA is a novel online intervention based on interventions for carers (Experienced Carers Helping Others, ECHO) and patients (Maudsley Model of Anorexia Nervosa Treatment for Adults, MANTRA) with anorexia nervosa. The objective of this paper is to describe the study protocol of a randomized control trial (RCT) aimed at evaluating the efficacy of an adaptation of the ECHOMANTRA for adults AN inpatients and outpatients, and their carers, to be implemented as an add-on to treatment-as-usual (TAU). Methods In a multi − center pilot randomized controlled trial (RCT), 148 adult AN patients, and their carers, will be randomized to receive treatment as usual (TAU) or TAU plus ECHOMANTRA. Assessments will take place at baseline (T0), post-intervention (2-month) (T1), 6-month follow-up (T2), and 12-month follow-up (T3). Primary outcomes will be eating disorder psychopathology and psychological well-being. For carers, outcome variables will include psychological well-being, accommodation and enabling behaviors, expressed emotion, illness burden, quality of life and care skills. Discussion This study will provide evidence of the efficacy of this novel, online and protocolized intervention in facilitating the recovery of these patients. Trial registration ISRCTN registry (Identifier: 80253157 https://doi.org/10.1186/ISRCTN80253157 ).https://doi.org/10.1186/s40337-024-01166-xRCTAdultAnorexia nervosaTreatmentECHOMANTRA |
| spellingShingle | Yolanda Quiles Álvaro Ruiz Eva León-Zarceño Javier Manchón Marie-Carmen Neipp Sofía Payá-López Katina Kovacheva Valentina Cardi Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial Journal of Eating Disorders RCT Adult Anorexia nervosa Treatment ECHO MANTRA |
| title | Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial |
| title_full | Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial |
| title_fullStr | Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial |
| title_full_unstemmed | Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial |
| title_short | Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial |
| title_sort | efficacy of the echomantra online intervention to support recovery from anorexia nervosa in adult patients study protocol of a randomized controlled multi center trial |
| topic | RCT Adult Anorexia nervosa Treatment ECHO MANTRA |
| url | https://doi.org/10.1186/s40337-024-01166-x |
| work_keys_str_mv | AT yolandaquiles efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT alvaroruiz efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT evaleonzarceno efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT javiermanchon efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT mariecarmenneipp efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT sofiapayalopez efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT katinakovacheva efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial AT valentinacardi efficacyoftheechomantraonlineinterventiontosupportrecoveryfromanorexianervosainadultpatientsstudyprotocolofarandomizedcontrolledmulticentertrial |