Primary Pancreatic Lymphoma Masquerading as Carcinoma

Adenocarcinoma is the most common primary pancreatic neoplasm type, followed by secondary pancreatic lymphoma and primary pancreatic lymphoma (PPL). PPL is associated with peripancreatic lymphadenopathy and usually presents as a homogenous mass with extrapancreatic invasion into surrounding structur...

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Main Author: Nasser A. N. Alzerwi
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2020/5160545
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author Nasser A. N. Alzerwi
author_facet Nasser A. N. Alzerwi
author_sort Nasser A. N. Alzerwi
collection DOAJ
description Adenocarcinoma is the most common primary pancreatic neoplasm type, followed by secondary pancreatic lymphoma and primary pancreatic lymphoma (PPL). PPL is associated with peripancreatic lymphadenopathy and usually presents as a homogenous mass with extrapancreatic invasion into surrounding structures. However, localized involvement of the distal pancreas is uncommon, and diffuse involvement of the pancreas is even rarer. Herein, we present the case of a 53-year-old woman with PPL of the uncinate process with biliary obstruction mimicking pancreatic adenocarcinoma, successfully diagnosed nonoperatively. Abdominal computed tomography showed an ill-defined uncinate process mass, hypodense with mild enhancement (3.9×3.4×3.5 cm), infiltrating the second and third parts of the duodenum. Biopsy revealed NHL with no evidence of adenocarcinoma. PPL was diagnosed. She received chemotherapy with a CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) protocol with rituximab, which she tolerated with no clinical or radiological evidence of recurrence at 1-year follow-up.
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spelling doaj-art-0a4eed75e5e1443ab519efa5e9f3bf512025-02-03T01:25:19ZengWileyCase Reports in Oncological Medicine2090-67062090-67142020-01-01202010.1155/2020/51605455160545Primary Pancreatic Lymphoma Masquerading as CarcinomaNasser A. N. Alzerwi0Department of Surgery, College of Medicine, Majmaah University, Ministry of Education, Al-Majmaah City, 11952, P. O. Box 66, Riyadh Region, Saudi ArabiaAdenocarcinoma is the most common primary pancreatic neoplasm type, followed by secondary pancreatic lymphoma and primary pancreatic lymphoma (PPL). PPL is associated with peripancreatic lymphadenopathy and usually presents as a homogenous mass with extrapancreatic invasion into surrounding structures. However, localized involvement of the distal pancreas is uncommon, and diffuse involvement of the pancreas is even rarer. Herein, we present the case of a 53-year-old woman with PPL of the uncinate process with biliary obstruction mimicking pancreatic adenocarcinoma, successfully diagnosed nonoperatively. Abdominal computed tomography showed an ill-defined uncinate process mass, hypodense with mild enhancement (3.9×3.4×3.5 cm), infiltrating the second and third parts of the duodenum. Biopsy revealed NHL with no evidence of adenocarcinoma. PPL was diagnosed. She received chemotherapy with a CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) protocol with rituximab, which she tolerated with no clinical or radiological evidence of recurrence at 1-year follow-up.http://dx.doi.org/10.1155/2020/5160545
spellingShingle Nasser A. N. Alzerwi
Primary Pancreatic Lymphoma Masquerading as Carcinoma
Case Reports in Oncological Medicine
title Primary Pancreatic Lymphoma Masquerading as Carcinoma
title_full Primary Pancreatic Lymphoma Masquerading as Carcinoma
title_fullStr Primary Pancreatic Lymphoma Masquerading as Carcinoma
title_full_unstemmed Primary Pancreatic Lymphoma Masquerading as Carcinoma
title_short Primary Pancreatic Lymphoma Masquerading as Carcinoma
title_sort primary pancreatic lymphoma masquerading as carcinoma
url http://dx.doi.org/10.1155/2020/5160545
work_keys_str_mv AT nasseranalzerwi primarypancreaticlymphomamasqueradingascarcinoma