Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer

Chylothorax presents as exudate with lymphocytic predominance and high triglyceride-low LDH levels, usually due to a traumatic disruption of the thoracic duct, possibly iatrogenic. Other causes include malignancy, sarcoidosis, goiter, AIDS, or tuberculosis. Here we present a case of a 66-year-old ma...

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Main Authors: Nooraldin Merza, John Lung, Mazin Saadaldin, Tarek Naguib
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2019/9387021
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author Nooraldin Merza
John Lung
Mazin Saadaldin
Tarek Naguib
author_facet Nooraldin Merza
John Lung
Mazin Saadaldin
Tarek Naguib
author_sort Nooraldin Merza
collection DOAJ
description Chylothorax presents as exudate with lymphocytic predominance and high triglyceride-low LDH levels, usually due to a traumatic disruption of the thoracic duct, possibly iatrogenic. Other causes include malignancy, sarcoidosis, goiter, AIDS, or tuberculosis. Here we present a case of a 66-year-old male who came in with cough and shortness of breath for few weeks. A week earlier, at an ED visit, he was diagnosed with pneumonia based on CT angiogram of the chest without contrast that showed bilateral pleural effusion and bilateral pulmonary infiltrates. The CT-guided placement of bilateral chest tube drained 1160 cc of creamy yellow fluid on the right and 1200 cc of creamy yellow fluid on the left. CT chest/abdomen/pelvis showed bilateral ground-glass opacities within the lungs and possible bony metastasis. A whole-body bone scan showed multiple bony metastatic lesions throughout the skeleton. IR guided bone biopsy suggested upper GI or pancreaticobiliary cancer. Venous ultrasound with Doppler of left upper extremity showed findings suggestive of a nonocclusive DVT of proximal/mid left subclavian vein which is difficult to compress. Eventually, malignancy-related DVT of the left subclavian/brachiocephalic vein was identified as the possible etiology for the bilateral chylothorax.
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spelling doaj-art-0a0889e2100c4c53ae6fb1890cc8ceb32025-02-03T06:45:57ZengWileyCase Reports in Pulmonology2090-68462090-68542019-01-01201910.1155/2019/93870219387021Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal CancerNooraldin Merza0John Lung1Mazin Saadaldin2Tarek Naguib3Department of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USASchool of Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USADepartment of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USADepartment of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USAChylothorax presents as exudate with lymphocytic predominance and high triglyceride-low LDH levels, usually due to a traumatic disruption of the thoracic duct, possibly iatrogenic. Other causes include malignancy, sarcoidosis, goiter, AIDS, or tuberculosis. Here we present a case of a 66-year-old male who came in with cough and shortness of breath for few weeks. A week earlier, at an ED visit, he was diagnosed with pneumonia based on CT angiogram of the chest without contrast that showed bilateral pleural effusion and bilateral pulmonary infiltrates. The CT-guided placement of bilateral chest tube drained 1160 cc of creamy yellow fluid on the right and 1200 cc of creamy yellow fluid on the left. CT chest/abdomen/pelvis showed bilateral ground-glass opacities within the lungs and possible bony metastasis. A whole-body bone scan showed multiple bony metastatic lesions throughout the skeleton. IR guided bone biopsy suggested upper GI or pancreaticobiliary cancer. Venous ultrasound with Doppler of left upper extremity showed findings suggestive of a nonocclusive DVT of proximal/mid left subclavian vein which is difficult to compress. Eventually, malignancy-related DVT of the left subclavian/brachiocephalic vein was identified as the possible etiology for the bilateral chylothorax.http://dx.doi.org/10.1155/2019/9387021
spellingShingle Nooraldin Merza
John Lung
Mazin Saadaldin
Tarek Naguib
Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer
Case Reports in Pulmonology
title Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer
title_full Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer
title_fullStr Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer
title_full_unstemmed Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer
title_short Bilateral Chylothorax as a Unique Presentation of Pancreaticobiliary or Upper Gastrointestinal Cancer
title_sort bilateral chylothorax as a unique presentation of pancreaticobiliary or upper gastrointestinal cancer
url http://dx.doi.org/10.1155/2019/9387021
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AT mazinsaadaldin bilateralchylothoraxasauniquepresentationofpancreaticobiliaryoruppergastrointestinalcancer
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