Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review

Background. Screening of children who are household contacts of tuberculosis (TB) cases is universally recommended but rarely implemented in TB endemic setting. This paper aims to summarise published data of the prevalence of TB infection and disease among child contacts in South East Asia. Methods....

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Main Authors: Rina Triasih, Merrin Rutherford, Trisasi Lestari, Adi Utarini, Colin F. Robertson, Stephen M. Graham
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2012/301808
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author Rina Triasih
Merrin Rutherford
Trisasi Lestari
Adi Utarini
Colin F. Robertson
Stephen M. Graham
author_facet Rina Triasih
Merrin Rutherford
Trisasi Lestari
Adi Utarini
Colin F. Robertson
Stephen M. Graham
author_sort Rina Triasih
collection DOAJ
description Background. Screening of children who are household contacts of tuberculosis (TB) cases is universally recommended but rarely implemented in TB endemic setting. This paper aims to summarise published data of the prevalence of TB infection and disease among child contacts in South East Asia. Methods. Search strategies were developed to identify all published studies from South East Asia of household contact investigation that included children (0–15 years). Results. Eleven studies were eligible for review. There was heterogeneity across the studies. TB infection was common among child contacts under 15 years of age (24.4–69.2%) and was higher than the prevalence of TB disease, which varied from 3.3% to 5.5%. Conclusion. TB infection is common among children that are household contacts of TB cases in South East Asia. Novel approaches to child contact screening and management that improve implementation in South East Asia need to be further evaluated.
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institution Kabale University
issn 1687-9686
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language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Journal of Tropical Medicine
spelling doaj-art-0a06030ddc9b4f709ec22e8564860cc12025-02-03T01:00:53ZengWileyJournal of Tropical Medicine1687-96861687-96942012-01-01201210.1155/2012/301808301808Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic ReviewRina Triasih0Merrin Rutherford1Trisasi Lestari2Adi Utarini3Colin F. Robertson4Stephen M. Graham5Department of Paediatrics, Faculty of Medicine, Gadjah Mada University, Yogyakarta 55284, IndonesiaCenter for International Health, University of Otago, Dunedin 9050, New ZealandDepartment of Public Health, Faculty of Medicine, Gadjah Mada University, Yogyakarta 55281, IndonesiaDepartment of Public Health, Faculty of Medicine, Gadjah Mada University, Yogyakarta 55281, IndonesiaDepartment of Respiratory Medicine, Royal Children's Hospital, Melbourne, VIC 3052, AustraliaCentre for International Child Health, Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children's Hospital, University of Melbourne, Melbourne, VIC 3052, AustraliaBackground. Screening of children who are household contacts of tuberculosis (TB) cases is universally recommended but rarely implemented in TB endemic setting. This paper aims to summarise published data of the prevalence of TB infection and disease among child contacts in South East Asia. Methods. Search strategies were developed to identify all published studies from South East Asia of household contact investigation that included children (0–15 years). Results. Eleven studies were eligible for review. There was heterogeneity across the studies. TB infection was common among child contacts under 15 years of age (24.4–69.2%) and was higher than the prevalence of TB disease, which varied from 3.3% to 5.5%. Conclusion. TB infection is common among children that are household contacts of TB cases in South East Asia. Novel approaches to child contact screening and management that improve implementation in South East Asia need to be further evaluated.http://dx.doi.org/10.1155/2012/301808
spellingShingle Rina Triasih
Merrin Rutherford
Trisasi Lestari
Adi Utarini
Colin F. Robertson
Stephen M. Graham
Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review
Journal of Tropical Medicine
title Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review
title_full Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review
title_fullStr Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review
title_full_unstemmed Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review
title_short Contact Investigation of Children Exposed to Tuberculosis in South East Asia: A Systematic Review
title_sort contact investigation of children exposed to tuberculosis in south east asia a systematic review
url http://dx.doi.org/10.1155/2012/301808
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