Deciphering signaling mechanisms and developmental dynamics in extraembryonic mesoderm specification from hESCs

Abstract Extraembryonic mesoderm (ExM) is crucial for human development, yet its specification is poorly understood. Human embryonic stem cell (hESC)-based models, including embryoids and differentiated derivatives, are emerging as promising tools for studying ExM development. Despite this, the sign...

Full description

Saved in:
Bibliographic Details
Main Authors: Baohua Niu, Da Wang, Yingjie Hu, Yundi Wang, Gaohui Shi, Zhongying Chen, Lifeng Xiang, Chi Zhang, Xuesong Wei, Ruize Kong, Hongzhi Cai, Weizhi Ji, Yu Yin, Tianqing Li, Zongyong Ai
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59491-x
Tags: Add Tag
No Tags, Be the first to tag this record!