A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia

Idiopathic thrombocytopenia (ITP) is a bleeding disorder involving the destruction of platelets by the immune system. Systemic amyloidosis is another bleeding disorder involving amyloid deposits that create defects in coagulation and increased prothrombin and thrombin times. We report a 52-year-old...

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Main Authors: Sung Han Kim, Weon Seo Park, Jae Young Joung, Kang Hyun Lee, Jinsoo Chung, Ho Kyung Seo
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2018/1059349
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author Sung Han Kim
Weon Seo Park
Jae Young Joung
Kang Hyun Lee
Jinsoo Chung
Ho Kyung Seo
author_facet Sung Han Kim
Weon Seo Park
Jae Young Joung
Kang Hyun Lee
Jinsoo Chung
Ho Kyung Seo
author_sort Sung Han Kim
collection DOAJ
description Idiopathic thrombocytopenia (ITP) is a bleeding disorder involving the destruction of platelets by the immune system. Systemic amyloidosis is another bleeding disorder involving amyloid deposits that create defects in coagulation and increased prothrombin and thrombin times. We report a 52-year-old man with ITP and new two-month-duration, painless gross hematuria without clot formation resulting in amyloidosis involving the ureterovesical area of the bladder. He had osteopenia, hypertension, and moderate thrombocytopenia due to ITP diagnosed 7 years previously. Cystoscopic examination with urine cytology and computed tomography imaging detected a 2-cm protruding solid bladder mass involving the left ureteral orifice and trigone and left mild hydroureteronephrosis, suggesting bladder cancer. Transurethral resection of the bladder mass was performed to confirm amyloidosis involvement in the ureterovesical junction of the bladder and ureter. Four weeks postoperatively, intermittent gross hematuria remained; hence, left ureteroneocystostomy was performed. Regular follow-up showed no signs of hematuria or intravesical recurrences for 14 months.
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series Case Reports in Urology
spelling doaj-art-09e66a8199aa4986b335152e84d72f912025-02-03T05:44:14ZengWileyCase Reports in Urology2090-696X2090-69782018-01-01201810.1155/2018/10593491059349A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic ThrombocytopeniaSung Han Kim0Weon Seo Park1Jae Young Joung2Kang Hyun Lee3Jinsoo Chung4Ho Kyung Seo5Department of Urology, Center for Prostate Cancer, National Cancer Center, Goyang, Republic of KoreaDepartment of Pathology, Center for Prostate Cancer, National Cancer Center, Goyang, Republic of KoreaDepartment of Urology, Center for Prostate Cancer, National Cancer Center, Goyang, Republic of KoreaDepartment of Urology, Center for Prostate Cancer, National Cancer Center, Goyang, Republic of KoreaDepartment of Urology, Center for Prostate Cancer, National Cancer Center, Goyang, Republic of KoreaDepartment of Urology, Center for Prostate Cancer, National Cancer Center, Goyang, Republic of KoreaIdiopathic thrombocytopenia (ITP) is a bleeding disorder involving the destruction of platelets by the immune system. Systemic amyloidosis is another bleeding disorder involving amyloid deposits that create defects in coagulation and increased prothrombin and thrombin times. We report a 52-year-old man with ITP and new two-month-duration, painless gross hematuria without clot formation resulting in amyloidosis involving the ureterovesical area of the bladder. He had osteopenia, hypertension, and moderate thrombocytopenia due to ITP diagnosed 7 years previously. Cystoscopic examination with urine cytology and computed tomography imaging detected a 2-cm protruding solid bladder mass involving the left ureteral orifice and trigone and left mild hydroureteronephrosis, suggesting bladder cancer. Transurethral resection of the bladder mass was performed to confirm amyloidosis involvement in the ureterovesical junction of the bladder and ureter. Four weeks postoperatively, intermittent gross hematuria remained; hence, left ureteroneocystostomy was performed. Regular follow-up showed no signs of hematuria or intravesical recurrences for 14 months.http://dx.doi.org/10.1155/2018/1059349
spellingShingle Sung Han Kim
Weon Seo Park
Jae Young Joung
Kang Hyun Lee
Jinsoo Chung
Ho Kyung Seo
A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia
Case Reports in Urology
title A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia
title_full A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia
title_fullStr A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia
title_full_unstemmed A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia
title_short A Surgically Treated Case of Ureterovesical Amyloidosis of the Bladder in a Patient with Idiopathic Thrombocytopenia
title_sort surgically treated case of ureterovesical amyloidosis of the bladder in a patient with idiopathic thrombocytopenia
url http://dx.doi.org/10.1155/2018/1059349
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