Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review
Necrotizing fasciitis is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. A 15-year-old primigravid woman, at 28 weeks of gestation with no significant previous medical history, was admitted to our hospital complaining of severe left lower extremit...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2014/505410 |
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| author | Marinos Nikolaou Petros Zampakis Vasiliki Vervita Konstantinos Almaloglou Georgios Adonakis Markos Marangos Georgios Decavalas |
| author_facet | Marinos Nikolaou Petros Zampakis Vasiliki Vervita Konstantinos Almaloglou Georgios Adonakis Markos Marangos Georgios Decavalas |
| author_sort | Marinos Nikolaou |
| collection | DOAJ |
| description | Necrotizing fasciitis is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. A 15-year-old primigravid woman, at 28 weeks of gestation with no significant previous medical history, was admitted to our hospital complaining of severe left lower extremity pain and high fever the last 72 hours. During clinical examination, she had a swollen, erythematous and tender to palpation inflamed skin over the medial aspect of the upper thigh without any evidence of injury. Incision drainage was performed immediately and she received broad spectrum antibiotics. During initial laboratory examinations, diabetes mellitus was diagnosed. There was no clinical improvement over the following days. Magnetic resonance imaging (MRI) revealed subcutaneous tissue inflammation and edema of infected tissues confirming the disease entity. Multidisciplinary therapy with immediate aggressive surgical debridement of necrotic tissues, multiple antibiotics, and intensive care monitoring was performed successfully. The patient’s postoperative course was uncomplicated and skin defect was closed with split thickness skin grafting. Our case emphasized the potential immunosuppressive role of pregnancy state in conjunction with diabetes mellitus in the development of severe necrotizing soft tissue infections. |
| format | Article |
| id | doaj-art-09cc37699e0b44eb845ad79633999e66 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-09cc37699e0b44eb845ad79633999e662025-02-03T01:12:42ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922014-01-01201410.1155/2014/505410505410Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature ReviewMarinos Nikolaou0Petros Zampakis1Vasiliki Vervita2Konstantinos Almaloglou3Georgios Adonakis4Markos Marangos5Georgios Decavalas6Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, GreeceDepartment of Radiology, Medical School, University of Patras, 26500 Patras, GreeceDepartment of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, GreeceDepartment of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, GreeceDepartment of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, GreeceDepartment of Internal Medicine, Division of Infectious Diseases, Medical School, University of Patras, 26500 Patras, GreeceDepartment of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, GreeceNecrotizing fasciitis is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. A 15-year-old primigravid woman, at 28 weeks of gestation with no significant previous medical history, was admitted to our hospital complaining of severe left lower extremity pain and high fever the last 72 hours. During clinical examination, she had a swollen, erythematous and tender to palpation inflamed skin over the medial aspect of the upper thigh without any evidence of injury. Incision drainage was performed immediately and she received broad spectrum antibiotics. During initial laboratory examinations, diabetes mellitus was diagnosed. There was no clinical improvement over the following days. Magnetic resonance imaging (MRI) revealed subcutaneous tissue inflammation and edema of infected tissues confirming the disease entity. Multidisciplinary therapy with immediate aggressive surgical debridement of necrotic tissues, multiple antibiotics, and intensive care monitoring was performed successfully. The patient’s postoperative course was uncomplicated and skin defect was closed with split thickness skin grafting. Our case emphasized the potential immunosuppressive role of pregnancy state in conjunction with diabetes mellitus in the development of severe necrotizing soft tissue infections.http://dx.doi.org/10.1155/2014/505410 |
| spellingShingle | Marinos Nikolaou Petros Zampakis Vasiliki Vervita Konstantinos Almaloglou Georgios Adonakis Markos Marangos Georgios Decavalas Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review Case Reports in Obstetrics and Gynecology |
| title | Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review |
| title_full | Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review |
| title_fullStr | Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review |
| title_full_unstemmed | Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review |
| title_short | Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review |
| title_sort | necrotizing fasciitis complicating pregnancy a case report and literature review |
| url | http://dx.doi.org/10.1155/2014/505410 |
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