The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis

Objective. To evaluate the effects of albuterol use in young infants admitted with respiratory syncytial virus (RSV) bronchiolitis with regards to length of time on supplemental oxygen and length of stay (LOS). To consider the possibility that albuterol use may increase the need for supplemental oxy...

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Main Authors: Michael T. Del Vecchio, Laura E. Doerr, John P. Gaughan
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Interdisciplinary Perspectives on Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2012/585901
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author Michael T. Del Vecchio
Laura E. Doerr
John P. Gaughan
author_facet Michael T. Del Vecchio
Laura E. Doerr
John P. Gaughan
author_sort Michael T. Del Vecchio
collection DOAJ
description Objective. To evaluate the effects of albuterol use in young infants admitted with respiratory syncytial virus (RSV) bronchiolitis with regards to length of time on supplemental oxygen and length of stay (LOS). To consider the possibility that albuterol use may increase the need for supplemental oxygen and increase LOS. Design, Setting, and Participants. Full-term infants between the ages of 11 days and 90 days (𝑁=316) were included in this retrospective study. Infants included were hospitalized with a diagnosis of RSV bronchiolitis at a university-affiliated children’s hospital. Results. In 4 of 5 severity groups, patients who received albuterol required more time on supplemental oxygen and had longer LOS. The differences only reached statistical significance in one of the severity groups in regards to LOS. Conclusions. The use of albuterol does not appear to be useful in the treatment of young infants with RSV bronchiolitis and may actually be harmful, in regards to increased supplemental oxygen need.
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spelling doaj-art-09c8453e71e3498691566eb23d6cb0c82025-02-03T01:04:55ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982012-01-01201210.1155/2012/585901585901The Use of Albuterol in Young Infants Hospitalized with Acute RSV BronchiolitisMichael T. Del Vecchio0Laura E. Doerr1John P. Gaughan2Department of Pediatrics, Temple University School of Medicine, Philadelphia, PA 19140, USADepartment of Pediatrics, Emory University, Atlanta, GA 30322, USADepartment of Epidemiology and Biostatistics, Temple University School of Medicine, Philadelphia, PA 19140, USAObjective. To evaluate the effects of albuterol use in young infants admitted with respiratory syncytial virus (RSV) bronchiolitis with regards to length of time on supplemental oxygen and length of stay (LOS). To consider the possibility that albuterol use may increase the need for supplemental oxygen and increase LOS. Design, Setting, and Participants. Full-term infants between the ages of 11 days and 90 days (𝑁=316) were included in this retrospective study. Infants included were hospitalized with a diagnosis of RSV bronchiolitis at a university-affiliated children’s hospital. Results. In 4 of 5 severity groups, patients who received albuterol required more time on supplemental oxygen and had longer LOS. The differences only reached statistical significance in one of the severity groups in regards to LOS. Conclusions. The use of albuterol does not appear to be useful in the treatment of young infants with RSV bronchiolitis and may actually be harmful, in regards to increased supplemental oxygen need.http://dx.doi.org/10.1155/2012/585901
spellingShingle Michael T. Del Vecchio
Laura E. Doerr
John P. Gaughan
The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis
Interdisciplinary Perspectives on Infectious Diseases
title The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis
title_full The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis
title_fullStr The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis
title_full_unstemmed The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis
title_short The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis
title_sort use of albuterol in young infants hospitalized with acute rsv bronchiolitis
url http://dx.doi.org/10.1155/2012/585901
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