Ocular Surface Temperature in Age-Related Macular Degeneration
Background. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/281010 |
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| author | Andrea Sodi Sara Matteoli Giovanni Giacomelli Lucia Finocchio Andrea Corvi Ugo Menchini |
| author_facet | Andrea Sodi Sara Matteoli Giovanni Giacomelli Lucia Finocchio Andrea Corvi Ugo Menchini |
| author_sort | Andrea Sodi |
| collection | DOAJ |
| description | Background. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37 eyes with atrophic AMD, 30 eyes affected by untreated neovascular AMD, and 43 eyes with fibrotic AMD were included. The control group consisted of 44 healthy eyes. Exclusion criteria were represented by any other ocular diseases other than AMD, tear film abnormalities, systemic cardiovascular abnormalities, diabetes mellitus, and a body temperature higher than 37.5°C. A total of 186 eyes without pupil dilation were investigated by infrared thermography (FLIR A320). The ocular surface temperature (OST) of three ocular points was calculated by means of an image processing technique from the infrared images. Two-sample t-test and one-way analysis of variance (ANOVA) test were used for statistical analyses. Results. ANOVA analyses showed no significant differences among AMD groups (P value >0.272). OST in AMD patients was significantly lower than in controls (P>0.05). Conclusions. Considering the possible relationship between ocular blood flow and OST, these findings might support the central role of ischemia in the pathogenesis of AMD. |
| format | Article |
| id | doaj-art-09c4661311d64e65bec725aece9e4d95 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-09c4661311d64e65bec725aece9e4d952025-02-03T01:13:04ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/281010281010Ocular Surface Temperature in Age-Related Macular DegenerationAndrea Sodi0Sara Matteoli1Giovanni Giacomelli2Lucia Finocchio3Andrea Corvi4Ugo Menchini5Department of Translational Surgery and Medicine, Eye Clinic, University of Florence, Largo Brambilla 3, 50134 Florence, ItalyLaboratory of Ocular Thermography, Department of Industrial Engineering, University of Florence, Florence, ItalyDepartment of Translational Surgery and Medicine, Eye Clinic, University of Florence, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Translational Surgery and Medicine, Eye Clinic, University of Florence, Largo Brambilla 3, 50134 Florence, ItalyLaboratory of Ocular Thermography, Department of Industrial Engineering, University of Florence, Florence, ItalyDepartment of Translational Surgery and Medicine, Eye Clinic, University of Florence, Largo Brambilla 3, 50134 Florence, ItalyBackground. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37 eyes with atrophic AMD, 30 eyes affected by untreated neovascular AMD, and 43 eyes with fibrotic AMD were included. The control group consisted of 44 healthy eyes. Exclusion criteria were represented by any other ocular diseases other than AMD, tear film abnormalities, systemic cardiovascular abnormalities, diabetes mellitus, and a body temperature higher than 37.5°C. A total of 186 eyes without pupil dilation were investigated by infrared thermography (FLIR A320). The ocular surface temperature (OST) of three ocular points was calculated by means of an image processing technique from the infrared images. Two-sample t-test and one-way analysis of variance (ANOVA) test were used for statistical analyses. Results. ANOVA analyses showed no significant differences among AMD groups (P value >0.272). OST in AMD patients was significantly lower than in controls (P>0.05). Conclusions. Considering the possible relationship between ocular blood flow and OST, these findings might support the central role of ischemia in the pathogenesis of AMD.http://dx.doi.org/10.1155/2014/281010 |
| spellingShingle | Andrea Sodi Sara Matteoli Giovanni Giacomelli Lucia Finocchio Andrea Corvi Ugo Menchini Ocular Surface Temperature in Age-Related Macular Degeneration Journal of Ophthalmology |
| title | Ocular Surface Temperature in Age-Related Macular Degeneration |
| title_full | Ocular Surface Temperature in Age-Related Macular Degeneration |
| title_fullStr | Ocular Surface Temperature in Age-Related Macular Degeneration |
| title_full_unstemmed | Ocular Surface Temperature in Age-Related Macular Degeneration |
| title_short | Ocular Surface Temperature in Age-Related Macular Degeneration |
| title_sort | ocular surface temperature in age related macular degeneration |
| url | http://dx.doi.org/10.1155/2014/281010 |
| work_keys_str_mv | AT andreasodi ocularsurfacetemperatureinagerelatedmaculardegeneration AT saramatteoli ocularsurfacetemperatureinagerelatedmaculardegeneration AT giovannigiacomelli ocularsurfacetemperatureinagerelatedmaculardegeneration AT luciafinocchio ocularsurfacetemperatureinagerelatedmaculardegeneration AT andreacorvi ocularsurfacetemperatureinagerelatedmaculardegeneration AT ugomenchini ocularsurfacetemperatureinagerelatedmaculardegeneration |