The Canadian Multicentre MAC Treatment Study
Mycobacierium avium complex (MAC) infeclion is a common complication of the advanced stages of human immunodeficiency virus (HIV) infection causing both morbidity and premature mortality. While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. th...
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Format: | Article |
Language: | English |
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Wiley
1994-01-01
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Series: | Canadian Journal of Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/1994/475109 |
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author | Stephen D Shafran The Canadian HIV Trials Network |
author_facet | Stephen D Shafran The Canadian HIV Trials Network |
author_sort | Stephen D Shafran |
collection | DOAJ |
description | Mycobacierium avium complex (MAC) infeclion is a common complication of the advanced stages of human immunodeficiency virus (HIV) infection
causing both morbidity and premature mortality. While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. the optimal regimen has not been defined. A Canadian Multicentre MAC Treatment Trial was proposed in 1990 and finally implemented in late 1992 via the Canadian HIV Trials Network with the assistance of 6 pharmaceutical companies. The specific drug regimens and study design are outlined and the timetable for analysis and completion are also indicated.
Collaborative, Canadian, multicentre clinical trials in HIV disease can be successfully implemented. |
format | Article |
id | doaj-art-09c1f309b37f41818c25de1d3e8079a7 |
institution | Kabale University |
issn | 1180-2332 |
language | English |
publishDate | 1994-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Infectious Diseases |
spelling | doaj-art-09c1f309b37f41818c25de1d3e8079a72025-02-03T01:31:06ZengWileyCanadian Journal of Infectious Diseases1180-23321994-01-015Suppl B21B23B10.1155/1994/475109The Canadian Multicentre MAC Treatment StudyStephen D Shafran0The Canadian HIV Trials Network1Division of Infectious Diseases, Department of Medicine, University of Alberta, and the Canadian HIV Trials Network, CanadaDivision of Infectious Diseases, Department of Medicine, University of Alberta, and the Canadian HIV Trials Network, CanadaMycobacierium avium complex (MAC) infeclion is a common complication of the advanced stages of human immunodeficiency virus (HIV) infection causing both morbidity and premature mortality. While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. the optimal regimen has not been defined. A Canadian Multicentre MAC Treatment Trial was proposed in 1990 and finally implemented in late 1992 via the Canadian HIV Trials Network with the assistance of 6 pharmaceutical companies. The specific drug regimens and study design are outlined and the timetable for analysis and completion are also indicated. Collaborative, Canadian, multicentre clinical trials in HIV disease can be successfully implemented.http://dx.doi.org/10.1155/1994/475109 |
spellingShingle | Stephen D Shafran The Canadian HIV Trials Network The Canadian Multicentre MAC Treatment Study Canadian Journal of Infectious Diseases |
title | The Canadian Multicentre MAC Treatment Study |
title_full | The Canadian Multicentre MAC Treatment Study |
title_fullStr | The Canadian Multicentre MAC Treatment Study |
title_full_unstemmed | The Canadian Multicentre MAC Treatment Study |
title_short | The Canadian Multicentre MAC Treatment Study |
title_sort | canadian multicentre mac treatment study |
url | http://dx.doi.org/10.1155/1994/475109 |
work_keys_str_mv | AT stephendshafran thecanadianmulticentremactreatmentstudy AT thecanadianhivtrialsnetwork thecanadianmulticentremactreatmentstudy AT stephendshafran canadianmulticentremactreatmentstudy AT thecanadianhivtrialsnetwork canadianmulticentremactreatmentstudy |