The Canadian Multicentre MAC Treatment Study

Mycobacierium avium complex (MAC) infeclion is a common complication of the advanced stages of human immunodeficiency virus (HIV) infection causing both morbidity and premature mortality. While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. th...

Full description

Saved in:
Bibliographic Details
Main Authors: Stephen D Shafran, The Canadian HIV Trials Network
Format: Article
Language:English
Published: Wiley 1994-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1994/475109
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832558980029743104
author Stephen D Shafran
The Canadian HIV Trials Network
author_facet Stephen D Shafran
The Canadian HIV Trials Network
author_sort Stephen D Shafran
collection DOAJ
description Mycobacierium avium complex (MAC) infeclion is a common complication of the advanced stages of human immunodeficiency virus (HIV) infection causing both morbidity and premature mortality. While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. the optimal regimen has not been defined. A Canadian Multicentre MAC Treatment Trial was proposed in 1990 and finally implemented in late 1992 via the Canadian HIV Trials Network with the assistance of 6 pharmaceutical companies. The specific drug regimens and study design are outlined and the timetable for analysis and completion are also indicated. Collaborative, Canadian, multicentre clinical trials in HIV disease can be successfully implemented.
format Article
id doaj-art-09c1f309b37f41818c25de1d3e8079a7
institution Kabale University
issn 1180-2332
language English
publishDate 1994-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases
spelling doaj-art-09c1f309b37f41818c25de1d3e8079a72025-02-03T01:31:06ZengWileyCanadian Journal of Infectious Diseases1180-23321994-01-015Suppl B21B23B10.1155/1994/475109The Canadian Multicentre MAC Treatment StudyStephen D Shafran0The Canadian HIV Trials Network1Division of Infectious Diseases, Department of Medicine, University of Alberta, and the Canadian HIV Trials Network, CanadaDivision of Infectious Diseases, Department of Medicine, University of Alberta, and the Canadian HIV Trials Network, CanadaMycobacierium avium complex (MAC) infeclion is a common complication of the advanced stages of human immunodeficiency virus (HIV) infection causing both morbidity and premature mortality. While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. the optimal regimen has not been defined. A Canadian Multicentre MAC Treatment Trial was proposed in 1990 and finally implemented in late 1992 via the Canadian HIV Trials Network with the assistance of 6 pharmaceutical companies. The specific drug regimens and study design are outlined and the timetable for analysis and completion are also indicated. Collaborative, Canadian, multicentre clinical trials in HIV disease can be successfully implemented.http://dx.doi.org/10.1155/1994/475109
spellingShingle Stephen D Shafran
The Canadian HIV Trials Network
The Canadian Multicentre MAC Treatment Study
Canadian Journal of Infectious Diseases
title The Canadian Multicentre MAC Treatment Study
title_full The Canadian Multicentre MAC Treatment Study
title_fullStr The Canadian Multicentre MAC Treatment Study
title_full_unstemmed The Canadian Multicentre MAC Treatment Study
title_short The Canadian Multicentre MAC Treatment Study
title_sort canadian multicentre mac treatment study
url http://dx.doi.org/10.1155/1994/475109
work_keys_str_mv AT stephendshafran thecanadianmulticentremactreatmentstudy
AT thecanadianhivtrialsnetwork thecanadianmulticentremactreatmentstudy
AT stephendshafran canadianmulticentremactreatmentstudy
AT thecanadianhivtrialsnetwork canadianmulticentremactreatmentstudy