Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte ce...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/8100423 |
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| author | Sangam Shah Rajeev Ojha Sanjeeta Sitaula Dosti Regmi Ragesh Karn Bikram Prasad Gajurel Reema Rajbhandari Niraj Gautam Sunanda Paudel Aashish Shrestha |
| author_facet | Sangam Shah Rajeev Ojha Sanjeeta Sitaula Dosti Regmi Ragesh Karn Bikram Prasad Gajurel Reema Rajbhandari Niraj Gautam Sunanda Paudel Aashish Shrestha |
| author_sort | Sangam Shah |
| collection | DOAJ |
| description | Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte cell surface and on the outermost cell surface of the myelin sheath may also be present in patients with NMOSD bilateral optic neuritis. Here, we describe a case of a thirty-nine-year-old-female with recurrent bilateral optic neuritis with positive anti-MOG antibody, and anti-MOG syndrome has not previously been reported from Nepal. |
| format | Article |
| id | doaj-art-09a31296f0474ffa83c2013c239ef399 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-09a31296f0474ffa83c2013c239ef3992025-02-03T01:27:24ZengWileyCase Reports in Neurological Medicine2090-66682090-66762021-01-01202110.1155/2021/81004238100423Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from NepalSangam Shah0Rajeev Ojha1Sanjeeta Sitaula2Dosti Regmi3Ragesh Karn4Bikram Prasad Gajurel5Reema Rajbhandari6Niraj Gautam7Sunanda Paudel8Aashish Shrestha9Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Ophthalmology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Radiology, Kanti Children's Hospital, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, NepalNeuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte cell surface and on the outermost cell surface of the myelin sheath may also be present in patients with NMOSD bilateral optic neuritis. Here, we describe a case of a thirty-nine-year-old-female with recurrent bilateral optic neuritis with positive anti-MOG antibody, and anti-MOG syndrome has not previously been reported from Nepal.http://dx.doi.org/10.1155/2021/8100423 |
| spellingShingle | Sangam Shah Rajeev Ojha Sanjeeta Sitaula Dosti Regmi Ragesh Karn Bikram Prasad Gajurel Reema Rajbhandari Niraj Gautam Sunanda Paudel Aashish Shrestha Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal Case Reports in Neurological Medicine |
| title | Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal |
| title_full | Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal |
| title_fullStr | Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal |
| title_full_unstemmed | Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal |
| title_short | Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal |
| title_sort | recurrent bilateral optic neuritis associated with myelin oligodendrocyte glycoprotein antibody a case report from nepal |
| url | http://dx.doi.org/10.1155/2021/8100423 |
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