The increased matrix stiffness caused by LOXL2 activates Piezo1 channels to promote the migration and invasion of cervical cancer cells
Abstract Background Lymph node metastasis in cervical cancer (CC) is a significant contributor to mortality associated with this disease. Notably, CC with lymph node metastasis exhibits greater stiffness upon palpation compared to CC without such metastasis. Lysyl oxidase-like 2 (LOXL2), a member of...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02456-9 |
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