Population Pharmacokinetics of Enrofloxacin in <i>Micropterus salmoides</i> Based on a Nonlinear Mixed Effect Model After Intravenous and Oral Administration

Population Pharmacokinetics of Enrofloxacin in <i>Micropterus salmoides</i> Based on a Nonlinear Mixed Effect Model After Intravenous and Oral Administration

This study aimed to investigate the PPK of EF in largemouth bass after oral and intravenous administration based on a nonlinear mixed effect model. Samples were collected using the sparse sampling method at pre-designed time points determined by high-performance liquid chromatography with a fluoresc...

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Bibliographic Details
Main Authors: Ning Xu, Shun Zhou, Jing Dong, Jiangtao Li, Yongzhen Ding, Xiaohui Ai
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Animals
Subjects:
enrofloxacin
population pharmacokinetics
statistical approaches
largemouth bass
body weight
Online Access:https://www.mdpi.com/2076-2615/15/10/1362
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