SPT6 regulates H3K14Ac deposition in mouse embryonic stem cells

SPT6 regulates H3K14Ac deposition in mouse embryonic stem cells

Summary: SPT6 (suppressor of Ty 6) is a conserved histone chaperone that plays critical roles in RNA Pol II progression and nucleosome reassembly. However, the functions of SPT6 in chromatin regulation remain incompletely understood. Here, we show that SPT6 localizes to histone H3 lysine 14 acetylat...

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Main Authors: Daixuan Zhang, Li Dong, Ying Cai, Peng Zhao, Qingqing Cai, Jian Zhang, Yajun Hu, Mandi Mu, Siyi Cheng, Jin Wang, Min Zeng, Chenxi He, Lei Zhang, Hui Yang, Fei Xavier Chen, Li Tan, Feizhen Wu, Yujiang Geno Shi, Wenqi Xu, Hongjie Shen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Reports
Subjects:
CP: Stem cell research
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725005285
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