Suppression of Leukotriene B4 Generation by Ex-vivo Neutrophils Isolated from Asthma Patients on Dietary Supplementation with Gammalinolenic Acid-containing Borage Oil: Possible Implication in Asthma

Dietary gammalinolenic acid (GLA), a potent inhibitor of 5-lipoxygenase (5-LOX) and suppressor of leukotriene B4 (LTB4), can attenuate the clinical course of rheumatoid arthritics, with negligible side effects. Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable sid...

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Bibliographic Details
Main Authors: Vincent A. Ziboh, Stanley Naguwa, Kao Vang, Julie Wineinger, Brian M. Morrissey, J. A. McIntyre, Mitchell Watnik, M. Eric Gershwin
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1080/10446670410001670445
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