Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology

The novel coronavirus pandemic has stimulated the scientific activity of virology and interdisciplinary sciences: medical cybernetics and bioinformatics. The article is focused on the study of algorithms for processing bioinformatic data of genomic origin predominantly for the purposes of predominan...

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Main Authors: M. V. Sprindzuk, A. S. Vladyko, L. P. Titov, Lu Zhuozhuang, V. I. Bernik
Format: Article
Language:Russian
Published: Ministry of Education of the Republic of Belarus, Establishment The Main Information and Analytical Center 2022-06-01
Series:Цифровая трансформация
Subjects:
Online Access:https://dt.bsuir.by/jour/article/view/663
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author M. V. Sprindzuk
A. S. Vladyko
L. P. Titov
Lu Zhuozhuang
V. I. Bernik
author_facet M. V. Sprindzuk
A. S. Vladyko
L. P. Titov
Lu Zhuozhuang
V. I. Bernik
author_sort M. V. Sprindzuk
collection DOAJ
description The novel coronavirus pandemic has stimulated the scientific activity of virology and interdisciplinary sciences: medical cybernetics and bioinformatics. The article is focused on the study of algorithms for processing bioinformatic data of genomic origin predominantly for the purposes of predominantly immunoinformatics and computational vaccinology. The schemes of algorithms developed by the authors for the analysis of bioinformatic data are presented. The algorithms for processing genomic information developed by the authors based on the analysis of the available literature and many years of experience in computational and laboratory experiments can be used not only for the design and analysis of epitope vaccine components, but also for the other tasks of computational virology and microbiology. In silico experiments on the analysis of bioinformatic data are relatively low-cost and multi-informative, but they require highly qualified scientists with extensive experience, interdisciplinary training, and, accordingly, a wide range of knowledge and skills. However, for the complete analysis and implementation of, for example, the epitope vaccines, subsequent validation by the laboratory and in vivo experiments are required.
format Article
id doaj-art-091e2245d8594cc9b6837ae7ac14ec59
institution Kabale University
issn 2522-9613
2524-2822
language Russian
publishDate 2022-06-01
publisher Ministry of Education of the Republic of Belarus, Establishment The Main Information and Analytical Center
record_format Article
series Цифровая трансформация
spelling doaj-art-091e2245d8594cc9b6837ae7ac14ec592025-02-03T05:39:03ZrusMinistry of Education of the Republic of Belarus, Establishment The Main Information and Analytical CenterЦифровая трансформация2522-96132524-28222022-06-01281718110.35596/2522-9613-2022-28-1-71-81265Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and VirologyM. V. Sprindzuk0A. S. Vladyko1L. P. Titov2Lu Zhuozhuang3V. I. Bernik4National Academy of Sciences of BelarusBelarus Ministry of HealthcareRRPC for epidemiology and microbiologyChinese Center for Disease Control and PreventionState Scientific Institution «Institute of Mathematics of the National Academy of Sciences of Belarus»The novel coronavirus pandemic has stimulated the scientific activity of virology and interdisciplinary sciences: medical cybernetics and bioinformatics. The article is focused on the study of algorithms for processing bioinformatic data of genomic origin predominantly for the purposes of predominantly immunoinformatics and computational vaccinology. The schemes of algorithms developed by the authors for the analysis of bioinformatic data are presented. The algorithms for processing genomic information developed by the authors based on the analysis of the available literature and many years of experience in computational and laboratory experiments can be used not only for the design and analysis of epitope vaccine components, but also for the other tasks of computational virology and microbiology. In silico experiments on the analysis of bioinformatic data are relatively low-cost and multi-informative, but they require highly qualified scientists with extensive experience, interdisciplinary training, and, accordingly, a wide range of knowledge and skills. However, for the complete analysis and implementation of, for example, the epitope vaccines, subsequent validation by the laboratory and in vivo experiments are required.https://dt.bsuir.by/jour/article/view/663sars-cov-2covid-19coronavirusepidemicpandemicautomated data processing systemssoftwaremedical cyberneticsgenomicstranscriptomicsmedical systemsimmunoinformatics
spellingShingle M. V. Sprindzuk
A. S. Vladyko
L. P. Titov
Lu Zhuozhuang
V. I. Bernik
Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology
Цифровая трансформация
sars-cov-2
covid-19
coronavirus
epidemic
pandemic
automated data processing systems
software
medical cybernetics
genomics
transcriptomics
medical systems
immunoinformatics
title Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology
title_full Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology
title_fullStr Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology
title_full_unstemmed Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology
title_short Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology
title_sort algorithms for processing coronavirus genomes for the goals and objectives of modern immunoinformatics vaccinomics and virology
topic sars-cov-2
covid-19
coronavirus
epidemic
pandemic
automated data processing systems
software
medical cybernetics
genomics
transcriptomics
medical systems
immunoinformatics
url https://dt.bsuir.by/jour/article/view/663
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AT lptitov algorithmsforprocessingcoronavirusgenomesforthegoalsandobjectivesofmodernimmunoinformaticsvaccinomicsandvirology
AT luzhuozhuang algorithmsforprocessingcoronavirusgenomesforthegoalsandobjectivesofmodernimmunoinformaticsvaccinomicsandvirology
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