Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis

Conclusions: Our findings suggest that gene expression changes induced by smoking in blood may contribute to the heightened risk of AMI. These identified genes are likely to play critical roles in the pathogenesis of AMI. Given the accessibility of peripheral blood samples, the expression levels of...

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Main Authors: Fang-Fang Liu, Yi-Xuan Yan, Hong-Feng Zhang, Ke Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/mi/2431090
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author Fang-Fang Liu
Yi-Xuan Yan
Hong-Feng Zhang
Ke Li
author_facet Fang-Fang Liu
Yi-Xuan Yan
Hong-Feng Zhang
Ke Li
author_sort Fang-Fang Liu
collection DOAJ
description Conclusions: Our findings suggest that gene expression changes induced by smoking in blood may contribute to the heightened risk of AMI. These identified genes are likely to play critical roles in the pathogenesis of AMI. Given the accessibility of peripheral blood samples, the expression levels of these genes could potentially serve as biomarkers for assessing cardiovascular health, particularly in individuals with a history of long-term exposure to cigarette smoke.
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institution Kabale University
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publishDate 2025-01-01
publisher Wiley
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series Mediators of Inflammation
spelling doaj-art-091e072a02e14656898534fd6be7fb792025-01-23T05:00:02ZengWileyMediators of Inflammation1466-18612025-01-01202510.1155/mi/2431090Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome AnalysisFang-Fang Liu0Yi-Xuan Yan1Hong-Feng Zhang2Ke Li3Department of PathologyDepartment of Blood TransfusionDepartment of PathologyDepartment of Blood TransfusionConclusions: Our findings suggest that gene expression changes induced by smoking in blood may contribute to the heightened risk of AMI. These identified genes are likely to play critical roles in the pathogenesis of AMI. Given the accessibility of peripheral blood samples, the expression levels of these genes could potentially serve as biomarkers for assessing cardiovascular health, particularly in individuals with a history of long-term exposure to cigarette smoke.http://dx.doi.org/10.1155/mi/2431090
spellingShingle Fang-Fang Liu
Yi-Xuan Yan
Hong-Feng Zhang
Ke Li
Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis
Mediators of Inflammation
title Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis
title_full Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis
title_fullStr Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis
title_full_unstemmed Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis
title_short Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis
title_sort gene expression signatures of smoking and acute myocardial infarction a blood transcriptome analysis
url http://dx.doi.org/10.1155/mi/2431090
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