Brain tissue oxidative damage as a possible mechanism for the deleterious effect of a chronic high dose of estradiol on learning and memory in ovariectomized rats Dano oxidativo ao tecido cerebral como possível mecanismo de efeito deletério da alta dose crônica de estradiol no aprendizado e memória de ratas ooforectomizadas

Brain tissue oxidative damage as a possible mechanism for the deleterious effect of a chronic high dose of estradiol on learning and memory in ovariectomized rats Dano oxidativo ao tecido cerebral como possível mecanismo de efeito deletério da alta dose crônica de estradiol no aprendizado e memória de ratas ooforectomizadas

In addition to antioxidative effects, estrogens also exert pro-oxidative actions. The effect of chronic administration of a high dose of estradiol valerate on Morris water maze tasks and brain tissues oxidative damage was investigated. The Sham-Est and OVX-Est groups were treated with estradiol vale...

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Bibliographic Details
Main Authors: Fatimeh Khodabandehloo, Mahmoud Hosseini, Ziba Rajaei, Mohammad Soukhtanloo, Esmaeil Farrokhi, Mohsen Rezaeipour
Format: Article
Language:English
Published: Thieme Revinter Publicações 2013-05-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
aprendizado
memória
ovariectomia
estradiol
Labirinto Aquático de Morris
estresse oxidativo
learning
memory
ovariectomy
morris water maze
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000500313
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