EPO Deficiency Upregulates GADD45b/p38 MAPK Axis, Mediating Schizophrenia‐Related Synaptic and Cognitive Impairments

EPO Deficiency Upregulates GADD45b/p38 MAPK Axis, Mediating Schizophrenia‐Related Synaptic and Cognitive Impairments

Abstract Schizophrenia (SZ) is a chronic and severe mental illness associated with psychiatric symptoms, cognitive deficits, and social dysfunction. Current clinical interventions only limit relief of psychiatric symptoms and have minimal impact on cognitive impairments. Erythropoietin (EPO), known...

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Bibliographic Details
Main Authors: Cuiping Guo, Wensheng Li, Yi Liu, Xiaoqing Tao, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Shusheng Li, Xiaochuan Wang
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
cognitive impairments
erythropoietin
GADD45b, p38 MAPK
schizophrenia
Online Access:https://doi.org/10.1002/advs.202406979
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