Personalized Genetic Testing and Norovirus Susceptibility
BACKGROUND: The availability of direct-to-consumer personalized genetic testing has enabled the public to access and interpret their own genetic information. Various genetic traits can be determined including resistance to norovirus through a nonsense mutation (G428A) in the FUT2 gene. Although this...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2014/708579 |
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| _version_ | 1832560783152644096 |
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| author | Natalie Prystajecky Fiona SL Brinkman Brian Auk Judith L Isaac-Renton Patrick Tang |
| author_facet | Natalie Prystajecky Fiona SL Brinkman Brian Auk Judith L Isaac-Renton Patrick Tang |
| author_sort | Natalie Prystajecky |
| collection | DOAJ |
| description | BACKGROUND: The availability of direct-to-consumer personalized genetic testing has enabled the public to access and interpret their own genetic information. Various genetic traits can be determined including resistance to norovirus through a nonsense mutation (G428A) in the FUT2 gene. Although this trait is believed to confer resistance to the most dominant norovirus genotype (GII.4), the spectrum of resistance to other norovirus strains is unknown. The present report describes a cluster of symptomatic norovirus GI.6 infection in a family identified to have norovirus resistance through personalized genetic testing. |
| format | Article |
| id | doaj-art-08f4ddd3f0d34acb9660eb26849de181 |
| institution | Kabale University |
| issn | 1712-9532 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-08f4ddd3f0d34acb9660eb26849de1812025-02-03T01:26:41ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322014-01-0125422222410.1155/2014/708579Personalized Genetic Testing and Norovirus SusceptibilityNatalie Prystajecky0Fiona SL Brinkman1Brian Auk2Judith L Isaac-Renton3Patrick Tang4British Columbia Public Health Microbiology and Reference Laboratory, Provincial Health Services Authority, CanadaDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, CanadaBritish Columbia Public Health Microbiology and Reference Laboratory, Provincial Health Services Authority, CanadaBritish Columbia Public Health Microbiology and Reference Laboratory, Provincial Health Services Authority, CanadaBritish Columbia Public Health Microbiology and Reference Laboratory, Provincial Health Services Authority, CanadaBACKGROUND: The availability of direct-to-consumer personalized genetic testing has enabled the public to access and interpret their own genetic information. Various genetic traits can be determined including resistance to norovirus through a nonsense mutation (G428A) in the FUT2 gene. Although this trait is believed to confer resistance to the most dominant norovirus genotype (GII.4), the spectrum of resistance to other norovirus strains is unknown. The present report describes a cluster of symptomatic norovirus GI.6 infection in a family identified to have norovirus resistance through personalized genetic testing.http://dx.doi.org/10.1155/2014/708579 |
| spellingShingle | Natalie Prystajecky Fiona SL Brinkman Brian Auk Judith L Isaac-Renton Patrick Tang Personalized Genetic Testing and Norovirus Susceptibility Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Personalized Genetic Testing and Norovirus Susceptibility |
| title_full | Personalized Genetic Testing and Norovirus Susceptibility |
| title_fullStr | Personalized Genetic Testing and Norovirus Susceptibility |
| title_full_unstemmed | Personalized Genetic Testing and Norovirus Susceptibility |
| title_short | Personalized Genetic Testing and Norovirus Susceptibility |
| title_sort | personalized genetic testing and norovirus susceptibility |
| url | http://dx.doi.org/10.1155/2014/708579 |
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