Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
Objective To discuss the pathogens and drug resistance in continuous ambulatory peritoneal dialysis(CAPD)-related peritonitis.Methods The pathogens and drug resistance were retrospectively analyzed on 180 cases(327 cases/times) of CAPD-related peritonitis in our center from Jan2008 to May 2013.Resul...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2015-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57920949&Fpath=home&index=0 |
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| Summary: | Objective To discuss the pathogens and drug resistance in continuous ambulatory peritoneal dialysis(CAPD)-related peritonitis.Methods The pathogens and drug resistance were retrospectively analyzed on 180 cases(327 cases/times) of CAPD-related peritonitis in our center from Jan2008 to May 2013.Results Positive cultures were seen in 202 cases/times with culture positive rate being 61.77%.There were 154 cases/times of gram-positive cocci,including 123 cases/times(60.89%) of Staphylococcus aureus and coagulase-negative staphylococci.There were 38 cases/times of gram-negative bacilli,including 11 cases/times(5.45%) of E.coll There were 10 cases/times of fungi,including 7 cases/times(3.47%) of Candida.The drug-resistant rate of gram-positive bacteria to vancomycin was lowest(3.25%),followed by moxifloxacin(5.19%),rifampin(12.99%),gentamicin(35.71%) and levofloxacin(45.45%),and that to penicillin highest(84.42%).The drug-resistant rate of gram-negative bacteria to piperacillin/tazobactam was lowest(10.53%),followed by ceftazidime(23.68%),levofloxacin(26.32%),cefpiramide US(36.84%),and that to ampicillin/sulbactam was highest(50.00%).Of 54 cases of repeated infections(114 cases/times).72 cases/times were positive with the culture positive rate being 63.16%,including 63 cases/times of Gram-positive cocci,predominantly Staphylococcus aureus,accounting for 87.50%,and 9 cases/times of Gram-negative bacilli,predominantly Escherichia coli,accounting for 12.50%.The drug-resistant rate of Grampositive cocci to vancomycin was lowestCl.59%),followed by moxifloxacin(3.17%),levofloxacin(15.87%) and gentamicin(55.56%),and that to penicillin was highest(95.24%).The drug-resistant rate of Gram-negative bacilli to piperacillin/tazobactam was lowest(11.11%),followed by ceftazidime(22.22%),levofloxacin(33.33%),gentamicin(55.56%),and that to ampicillin/sulbactam was highest(88.89%).Conclusions The CAPD-related peritonitis in this center is mainly induced by Grampositive cocci Contact contamination is the main cause of peritonitis.The resistant rate of Gram-positive cocci to penicillin is highest,and that of Gram-negative bacilli to ampicillin/sulbactam is highest |
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| ISSN: | 1671-2390 |