Chloroquine Urea Derivatives: Synthesis and Antitumor Activity in Vitro
In the current paper, we describe the design, synthesis and antiproliferative screening of novel chloroquine derivatives with a quinoline core linked to a hydroxy or halogen amine through a flexible aminobutyl chain and urea spacer. Synthetic pathway leading to chloroquine urea derivatives 4-10 incl...
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Main Authors: | Pavić Kristina, Rajić Zrinka, Mlinarić Zvonimir, Uzelac Lidija, Kralj Marijeta, Zorc Branka |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2018-12-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2018-0039 |
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