The Association between Type 2 Diabetes Mellitus and Thyroid Cancer
Aim. The incidence of thyroid cancer is increasing worldwide. The prevalence of type 2 diabetes mellitus (T2DM) is also increasing. Therefore, we aimed to analyze the effect of T2DM on thyroid cancer. Methods. A case-control study was performed. A total of 415 healthy controls with thyroid ultrasoun...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2017/5850879 |
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| author | Young-Gyun Seo Ho-Chun Choi Ah Reum An Do Joon Park Young Joo Park Kyu Eun Lee Sue K. Park Yunji Hwang Belong Cho |
| author_facet | Young-Gyun Seo Ho-Chun Choi Ah Reum An Do Joon Park Young Joo Park Kyu Eun Lee Sue K. Park Yunji Hwang Belong Cho |
| author_sort | Young-Gyun Seo |
| collection | DOAJ |
| description | Aim. The incidence of thyroid cancer is increasing worldwide. The prevalence of type 2 diabetes mellitus (T2DM) is also increasing. Therefore, we aimed to analyze the effect of T2DM on thyroid cancer. Methods. A case-control study was performed. A total of 415 healthy controls with thyroid ultrasound screening and physician consultation were selected from the Thyroid Cancer Longitudinal Study (T-CALOS). Among patients with thyroid cancer who were enrolled in T-CALOS, 415 patients were matched to the control group according to age and sex. We assessed the effects of T2DM, T2DM duration, and T2DM medication on thyroid cancer. Results. Women with T2DM had lower odds of thyroid cancer than women without T2DM (odds ratio [OR]: 0.40, 95% confidence interval [CI]: 0.20–0.81). Individuals receiving T2DM medication had higher odds of thyroid cancer compared to those without T2DM medication (OR: 5.21, 95% CI: 1.58–17.15). Individuals with T2DM duration <6 years had lower odds of thyroid cancer compared to those without T2DM (OR: 0.58, 95% CI: 0.34–0.97). Conclusions. Individuals with early T2DM are presumed to have a low incidence of thyroid cancer, and this effect seems to last up to 6 years after diagnosis of T2DM. |
| format | Article |
| id | doaj-art-08b8d57ce8c448c18cdd45f7b217da1d |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-08b8d57ce8c448c18cdd45f7b217da1d2025-02-03T01:30:13ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/58508795850879The Association between Type 2 Diabetes Mellitus and Thyroid CancerYoung-Gyun Seo0Ho-Chun Choi1Ah Reum An2Do Joon Park3Young Joo Park4Kyu Eun Lee5Sue K. Park6Yunji Hwang7Belong Cho8Department of Family Medicine, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-do 14068, Republic of KoreaDepartment of Family Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul 03080, Republic of KoreaDepartment of Family Medicine, Center for Health Promotion and Optimal Aging, Health Promotion Center for Cancer Survivor, Seoul National University Hospital, Seoul 03080, Republic of KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of KoreaDepartment of Surgery, Seoul National University Hospital & College of Medicine, Seoul 03080, Republic of KoreaDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of KoreaDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of KoreaDepartment of Family Medicine, Center for Health Promotion and Optimal Aging, Health Promotion Center for Cancer Survivor, Seoul National University Hospital, Seoul 03080, Republic of KoreaAim. The incidence of thyroid cancer is increasing worldwide. The prevalence of type 2 diabetes mellitus (T2DM) is also increasing. Therefore, we aimed to analyze the effect of T2DM on thyroid cancer. Methods. A case-control study was performed. A total of 415 healthy controls with thyroid ultrasound screening and physician consultation were selected from the Thyroid Cancer Longitudinal Study (T-CALOS). Among patients with thyroid cancer who were enrolled in T-CALOS, 415 patients were matched to the control group according to age and sex. We assessed the effects of T2DM, T2DM duration, and T2DM medication on thyroid cancer. Results. Women with T2DM had lower odds of thyroid cancer than women without T2DM (odds ratio [OR]: 0.40, 95% confidence interval [CI]: 0.20–0.81). Individuals receiving T2DM medication had higher odds of thyroid cancer compared to those without T2DM medication (OR: 5.21, 95% CI: 1.58–17.15). Individuals with T2DM duration <6 years had lower odds of thyroid cancer compared to those without T2DM (OR: 0.58, 95% CI: 0.34–0.97). Conclusions. Individuals with early T2DM are presumed to have a low incidence of thyroid cancer, and this effect seems to last up to 6 years after diagnosis of T2DM.http://dx.doi.org/10.1155/2017/5850879 |
| spellingShingle | Young-Gyun Seo Ho-Chun Choi Ah Reum An Do Joon Park Young Joo Park Kyu Eun Lee Sue K. Park Yunji Hwang Belong Cho The Association between Type 2 Diabetes Mellitus and Thyroid Cancer Journal of Diabetes Research |
| title | The Association between Type 2 Diabetes Mellitus and Thyroid Cancer |
| title_full | The Association between Type 2 Diabetes Mellitus and Thyroid Cancer |
| title_fullStr | The Association between Type 2 Diabetes Mellitus and Thyroid Cancer |
| title_full_unstemmed | The Association between Type 2 Diabetes Mellitus and Thyroid Cancer |
| title_short | The Association between Type 2 Diabetes Mellitus and Thyroid Cancer |
| title_sort | association between type 2 diabetes mellitus and thyroid cancer |
| url | http://dx.doi.org/10.1155/2017/5850879 |
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