Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness

We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data t...

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Main Authors: G. Bartoli, G. Menegaz, M. Lisi, G. Di Stolfo, S. Dragoni, T. Gori
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2008/738545
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author G. Bartoli
G. Menegaz
M. Lisi
G. Di Stolfo
S. Dragoni
T. Gori
author_facet G. Bartoli
G. Menegaz
M. Lisi
G. Di Stolfo
S. Dragoni
T. Gori
author_sort G. Bartoli
collection DOAJ
description We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.
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series International Journal of Biomedical Imaging
spelling doaj-art-08b7e496ca594bb28cf0822ebb3bc1ef2025-02-03T05:50:20ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962008-01-01200810.1155/2008/738545738545Model-Based Analysis of Flow-Mediated Dilation and Intima-Media ThicknessG. Bartoli0G. Menegaz1M. Lisi2G. Di Stolfo3S. Dragoni4T. Gori5Department of Information Engineering, University of Siena, 53100 Siena, ItalyDepartment of Computer Science, University of Verona, 37134 Verona, ItalyDepartment of Internal, Cardiovascular, and Geriatric Medicine, University of Siena, 53100 Siena, ItalyDepartment of Internal, Cardiovascular, and Geriatric Medicine, University of Siena, 53100 Siena, ItalyDepartment of Internal, Cardiovascular, and Geriatric Medicine, University of Siena, 53100 Siena, ItalyMedizinische Klinik für Kardiologie und Angiologie, 55131 Mainz, GermanyWe present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data to detect the artery boundaries and track them all along the video sequence. The a priori knowledge about the image features and its content is exploited. Preprocessing is performed to improve both the visual quality of video frames for visual inspection and the performance of the segmentation algorithm without affecting the accuracy of the measurements. The system allows real-time processing as well as a high level of interactivity with the user. This is obtained by a graphical user interface (GUI) enabling the cardiologist to supervise the whole process and to eventually reset the contour extraction at any point in time. The system was validated and the accuracy, reproducibility, and repeatability of the measurements were assessed with extensive in vivo experiments. Jointly with the user friendliness, low cost, and robustness, this makes the system suitable for both research and daily clinical use.http://dx.doi.org/10.1155/2008/738545
spellingShingle G. Bartoli
G. Menegaz
M. Lisi
G. Di Stolfo
S. Dragoni
T. Gori
Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
International Journal of Biomedical Imaging
title Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
title_full Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
title_fullStr Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
title_full_unstemmed Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
title_short Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
title_sort model based analysis of flow mediated dilation and intima media thickness
url http://dx.doi.org/10.1155/2008/738545
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