The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure

Oliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial hypertension (ICH). The actual knowledge to explain this relationship is scarce. Almost all literature is about animals where authors describe the...

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Main Authors: K. Leyssens, T. Mortelmans, T. Menovsky, D. Abramowicz, Marcel Th. B. Twickler, L. Van Gaal
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2017/2582509
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author K. Leyssens
T. Mortelmans
T. Menovsky
D. Abramowicz
Marcel Th. B. Twickler
L. Van Gaal
author_facet K. Leyssens
T. Mortelmans
T. Menovsky
D. Abramowicz
Marcel Th. B. Twickler
L. Van Gaal
author_sort K. Leyssens
collection DOAJ
description Oliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial hypertension (ICH). The actual knowledge to explain this relationship is scarce. Almost all literature is about animals where authors describe the Cushing reflex in response to ICH. We hypothesize that the Cushing reflex is translated towards the sympathetic nervous system and renin-angiotensin-aldosterone system with a subsequent reduction in medullary blood flow and oliguria. Recently, we were confronted with a patient who had complicated pituitary surgery and displayed multiple times an oliguria while he developed ICH.
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institution Kabale University
issn 2090-6641
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language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Nephrology
spelling doaj-art-08ab75c31a2c426494ed9c3854e941092025-02-03T01:26:45ZengWileyCase Reports in Nephrology2090-66412090-665X2017-01-01201710.1155/2017/25825092582509The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial PressureK. Leyssens0T. Mortelmans1T. Menovsky2D. Abramowicz3Marcel Th. B. Twickler4L. Van Gaal5Department of Internal Medicine, University of Antwerp, Antwerp, BelgiumFaculty of Medicine, University of Antwerp, Antwerp, BelgiumDepartment of Neurosurgery, Antwerp University Hospital, Edegem, Antwerp, BelgiumDepartment of Nephrology, Antwerp University Hospital, Edegem, Antwerp, BelgiumDepartment of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Edegem, Antwerp, BelgiumDepartment of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Edegem, Antwerp, BelgiumOliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial hypertension (ICH). The actual knowledge to explain this relationship is scarce. Almost all literature is about animals where authors describe the Cushing reflex in response to ICH. We hypothesize that the Cushing reflex is translated towards the sympathetic nervous system and renin-angiotensin-aldosterone system with a subsequent reduction in medullary blood flow and oliguria. Recently, we were confronted with a patient who had complicated pituitary surgery and displayed multiple times an oliguria while he developed ICH.http://dx.doi.org/10.1155/2017/2582509
spellingShingle K. Leyssens
T. Mortelmans
T. Menovsky
D. Abramowicz
Marcel Th. B. Twickler
L. Van Gaal
The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
Case Reports in Nephrology
title The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_full The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_fullStr The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_full_unstemmed The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_short The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_sort cushing reflex oliguria as a reflection of an elevated intracranial pressure
url http://dx.doi.org/10.1155/2017/2582509
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