Some cyano-substituted spiro-linked pyrazolines and pyrrolidines with antimicrobial activity

Some cyano-substituted spiro-linked pyrazolines and pyrrolidines with antimicrobial activity

This work summarizes one-pot synthetic approaches to spiro-fused (di)azoles, which are promising in terms of studying biological activity. Proposed approaches involve condensation reactions of (hetero)cyclic ketones, methylene active moieties, and N-nucleophiles, occurring under mild conditions by b...

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Bibliographic Details
Main Authors:	Meshcheryakova, Anna A., Borisova, Svetlana Vasilievna, Konstantinova, Ekaterina A., Vidlatskaya, Daria V., Burygin, Gennady L., Sorokin, Vitaly Viktorovich
Format:	Article
Language:	English
Published:	Saratov State University 2024-12-01
Series:	Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология
Subjects:	spirooxoindoles isatin 1 3-dipolar cycloaddition azomethine ylides three-component reaction 3-amino-1 2-diazaspiro[4.5]non3-ene-4-carbonitriles 2-diazaspiro[4.5]deca-3-ene-4-carbonitriles
Online Access:	https://ichbe.sgu.ru/sites/ichbe.sgu.ru/files/text-pdf/2024/12/himiya_2024_4-374-379.pdf
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