Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia
Candida bloodstream infection is the major cause of increased morbidity and mortality (20–49%) in hospitalized patients in both paediatric and adult age groups. Due to the increase in the number of immunocompromised patients, other important species such as Trichosporon asahii and Debaryomyces hanse...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2020/8847853 |
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| author | Vibha Mehta Aroop Mohanty Suneeta Meena J. S. Rahul Nath Uttam Kumar Debranjani Chattopadhyay Anamika Bakliwal Ranjana Choudhary Pratima Gupta |
| author_facet | Vibha Mehta Aroop Mohanty Suneeta Meena J. S. Rahul Nath Uttam Kumar Debranjani Chattopadhyay Anamika Bakliwal Ranjana Choudhary Pratima Gupta |
| author_sort | Vibha Mehta |
| collection | DOAJ |
| description | Candida bloodstream infection is the major cause of increased morbidity and mortality (20–49%) in hospitalized patients in both paediatric and adult age groups. Due to the increase in the number of immunocompromised patients, other important species such as Trichosporon asahii and Debaryomyces hansenii are emerging. One such organism, Wickerhamomyces anomalous, previously known as Pichia anomala (teleomorph stages of several Candida species), is increasingly being reported as a cause of fungemia in neonatal intensive care units and is now increasingly being reported in a lot of immunosuppressive conditions such as interstitial lung disease, endocarditis, enteritis, corticosteroids, and chemotherapy uptake. Though this yeast is ubiquitous in nature, systemic infections from isolated cases and sporadic outbreaks with high mortality have been reported in ICUs, which emphasize the importance to consider this fungus within the diagnostic possibilities. Here, we report a case of catheter-related bloodstream infection (CRBSI) caused by W. anomalus in a leukemic immunosuppressed patient who was successfully treated by early detection and treatment of this emerging fungus. |
| format | Article |
| id | doaj-art-08795c9ac06a4794a1c8a8a5e7aa6cfc |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-08795c9ac06a4794a1c8a8a5e7aa6cfc2025-02-03T01:00:11ZengWileyCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/88478538847853Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic LeukemiaVibha Mehta0Aroop Mohanty1Suneeta Meena2J. S. Rahul3Nath Uttam Kumar4Debranjani Chattopadhyay5Anamika Bakliwal6Ranjana Choudhary7Pratima Gupta8PDCC Hepatic and Transplant Virology, ILBS, New Delhi, IndiaDepartment of Clinical Microbiology, AIIMS, Gorakhpur, IndiaDepartment of Laboratory Medicine, AIIMS, New Delhi, IndiaDepartment of Neuroanaesthesia and Critical Care, AIIMS, New Delhi, IndiaDepartment of Medical Oncology and Haematology, AIIMS Rishikesh, Rishikesh, IndiaDepartment of Medical Oncology and Haematology, AIIMS Rishikesh, Rishikesh, IndiaDepartment of Medical Oncology and Haematology, AIIMS Rishikesh, Rishikesh, IndiaDepartment of Microbiology, AIIMS Rishikesh, Rishikesh, IndiaDepartment of Microbiology, AIIMS Rishikesh, Rishikesh, IndiaCandida bloodstream infection is the major cause of increased morbidity and mortality (20–49%) in hospitalized patients in both paediatric and adult age groups. Due to the increase in the number of immunocompromised patients, other important species such as Trichosporon asahii and Debaryomyces hansenii are emerging. One such organism, Wickerhamomyces anomalous, previously known as Pichia anomala (teleomorph stages of several Candida species), is increasingly being reported as a cause of fungemia in neonatal intensive care units and is now increasingly being reported in a lot of immunosuppressive conditions such as interstitial lung disease, endocarditis, enteritis, corticosteroids, and chemotherapy uptake. Though this yeast is ubiquitous in nature, systemic infections from isolated cases and sporadic outbreaks with high mortality have been reported in ICUs, which emphasize the importance to consider this fungus within the diagnostic possibilities. Here, we report a case of catheter-related bloodstream infection (CRBSI) caused by W. anomalus in a leukemic immunosuppressed patient who was successfully treated by early detection and treatment of this emerging fungus.http://dx.doi.org/10.1155/2020/8847853 |
| spellingShingle | Vibha Mehta Aroop Mohanty Suneeta Meena J. S. Rahul Nath Uttam Kumar Debranjani Chattopadhyay Anamika Bakliwal Ranjana Choudhary Pratima Gupta Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia Case Reports in Infectious Diseases |
| title | Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia |
| title_full | Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia |
| title_fullStr | Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia |
| title_full_unstemmed | Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia |
| title_short | Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia |
| title_sort | wickerhamomyces anomalous a rare cause of fungemia causing febrile neutropenia in acute lymphoblastic leukemia |
| url | http://dx.doi.org/10.1155/2020/8847853 |
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