Parabrachial CGRP neurons modulate active defensive behavior under a naturalistic threat

Parabrachial CGRP neurons modulate active defensive behavior under a naturalistic threat

Recent studies suggest that calcitonin gene-related peptide (CGRP) neurons in the parabrachial nucleus (PBN) represent aversive information and signal a general alarm to the forebrain. If CGRP neurons serve as a true general alarm, their activation would modulate both passive nad active defensive be...

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Bibliographic Details
Main Authors: Gyeong Hee Pyeon, Hyewon Cho, Byung Min Chung, June-Seek Choi, Yong Sang Jo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
CGRP
fear conditioning
fleeing
freezing
parabrachial nucleus
defensive behavior
Online Access:https://elifesciences.org/articles/101523
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