Presence of Autoimmune Antibody in Chikungunya Infection
Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and sw...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2009/840183 |
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| _version_ | 1832550601554132992 |
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| author | Wirach Maek-a-nantawat Udomsak Silachamroon |
| author_facet | Wirach Maek-a-nantawat Udomsak Silachamroon |
| author_sort | Wirach Maek-a-nantawat |
| collection | DOAJ |
| description | Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators. |
| format | Article |
| id | doaj-art-0856b7788e1a453bb642b5e03fdaf99e |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-0856b7788e1a453bb642b5e03fdaf99e2025-02-03T06:06:13ZengWileyCase Reports in Medicine1687-96271687-96352009-01-01200910.1155/2009/840183840183Presence of Autoimmune Antibody in Chikungunya InfectionWirach Maek-a-nantawat0Udomsak Silachamroon1Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchavithi Rd., Ratchathewee 10400, Bangkok, ThailandDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchavithi Rd., Ratchathewee 10400, Bangkok, ThailandChikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators.http://dx.doi.org/10.1155/2009/840183 |
| spellingShingle | Wirach Maek-a-nantawat Udomsak Silachamroon Presence of Autoimmune Antibody in Chikungunya Infection Case Reports in Medicine |
| title | Presence of Autoimmune Antibody in Chikungunya Infection |
| title_full | Presence of Autoimmune Antibody in Chikungunya Infection |
| title_fullStr | Presence of Autoimmune Antibody in Chikungunya Infection |
| title_full_unstemmed | Presence of Autoimmune Antibody in Chikungunya Infection |
| title_short | Presence of Autoimmune Antibody in Chikungunya Infection |
| title_sort | presence of autoimmune antibody in chikungunya infection |
| url | http://dx.doi.org/10.1155/2009/840183 |
| work_keys_str_mv | AT wirachmaekanantawat presenceofautoimmuneantibodyinchikungunyainfection AT udomsaksilachamroon presenceofautoimmuneantibodyinchikungunyainfection |